- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB2218 Replaces AB3068 商名 - Chemicon
描述 Anti-Aquaporin 4 Antibody Alternate Names - MIWC
- AQP4
- WCH4
背景信息 The water-specific channel Aquaporin 4 is located in various tissues including the gastro intestinal tract, kidney and brain. It is an osmoreceptor which regulates body water balance and mediates water flow within the central nervous system. The localization of AQ4 to astrocyte endfeet makes it an excellent marker for astrocyte distal processes. 产品信息 格式 Affinity Purified 控制 - Tested on adult rat brain lysate
演示 Purified in PBS with 0.05% NaN3 应用 应用 Anti-Aquaporin 4 Antibody is an antibody against Aquaporin 4 for use in WB. 主要应用 - Western Blotting
应用说明 Western Blotting: 0.5-1 μg/mL using Chemiluminescence technique.
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Synthetic Linear Peptide 表位 C-Terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes Aquaporin 4. 品种反应性 RatHumanMouse Species Reactivity Note The antibody has not yet been tested for cross-reactivity to other species.
The immunogen shows 94% similarity to mouse, 88% to bovine, 86% to rabbit and 82% to human AQP4 (hAQP4).抗体类型 Polyclonal Antibody Entrez基因编号 - NM_004028.3
- NM_001650.4
Entrez基因汇总 This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. 基因符号 - MGC22454
- AQP4
- MIWC
- WCH4
- AQP-4
- aquaporin-4
- HMIWC2
- Aquaporin-4
纯化方法 Immunoaffinity purified UniProt编号 - P55087
UniProt汇总 FUNCTION: SwissProt: P55087 # Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.
SIZE: 323 amino acids; 34830 Da
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Brain - muscle > heart, kidney, lung, and trachea.
DOMAIN: SwissProt: P55087 Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,07-596,Anti-Histone H4 (citrulline 3) Antibody
下一件merck millipore产品：merck millipore,默克密理博,MAB011-A/13,Anti-Apolipoprotein A-I Antibody, clone A/13
相关产品
merck millipore,默克密理博,605211,Thrombin Substrate III, Fluorogenic - Calbiochem
merck millipore,默克密理博,557305,RNAi Enhancer, Enoxacin Sodium Salt - Calbiochem
merck millipore,默克密理博,574596,Anti-Superoxide Dismutase (Mn Enzyme) Sheep pAb
merck millipore,默克密理博,MABN763,Anti-Ubiquilin 2 Antibody, clone 6H9
merck millipore,默克密理博,07-596,Anti-Histone H4 (citrulline 3) Antibody
merck millipore,默克密理博,MAB011-A/13,Anti-Apolipoprotein A-I Antibody, clone A/13
merck millipore,默克密理博,516566,PPARγ Antagonist III, G3335 - CAS 36099-95-3 - Calbiochem
merck millipore,默克密理博,07-719,Anti-acetyl-H2A.Z (Lys14) Antibody
merck millipore,默克密理博,AB3252,Anti-c-myc Antibody
merck millipore,默克密理博,M04S-03-5PK,CellASIC ONIX switching plate mammalian cells (4 chamber)