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merck millipore,默克密理博,MABN674,Anti-PSIP1 Antibody, clone 6E4
产品名称：Anti-PSIP1 Antibody, clone 6E4
产品型号：MABN674
Detect PSIP1 using this mouse monoclonal antibody, Anti-PSIP1 Antibody, clone 6E4 validated for use in western blotting, IHC & Immunofluorescence.
merck millipore,默克密理博,MABN674,Anti-PSIP1 Antibody, clone 6E4
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, Mk IHC, WB M Ascites Monoclonal Antibody 描述 产品目录编号 MABN674 描述 Anti-PSIP1 Antibody, clone 6E4 Alternate Names - PSIP1 protein
背景信息 PSIP1, also known as coactivator p75, as well as numerous other synonyms named after their original discoveries including, PC4 and SFRS1 interacting protein 1, lens epithelium-derived growth factor (LEDGF/p75), dense fine speckles 70kD protein (DFS 70), and transcriptional coactivator p75/p52, is a transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. It is particularly important in lens epithelial cell gene regulation and stress responses, and even though initially thought to be limited to the lens of the eye, PSIP1 is now known to be widely expressed in most tissues and has no direct role in the development of lens epithelium. It also gained research interest as the focal point for HIV integration and appears to be one of the few integrase interactor proteins whose knockdown limits HIV integration and propagation. Moreover, PSIP1 is an anti-apoptotic protein and appears to play a protective role during stress-induced apoptosis. There are three isoforms of the PSIP1 in humans, PSIP1, PSIP2 or p52, and a third isoform which is unnamed. The PSIP1 isoforms seem to vary in their precise functions somewhat with isoform 2 being the most commonly expressed and most abundant. Expression is localized to the nucleus. EMD-Millipore’s anti-PSIP1mouse monoclonal, clone 6.00E+04 has been tested on human, paraffin embedded immunohistochemical sections, immunocytochemical immunofluorescence studies using mouse NIH3T3 cells, western blot using human, mouse, and rat cells line lysates, and ELISA using purified antigen. 产品信息 格式 Ascites 控制 - HepG2, Jurkat, K562, Cos7, PC-12, HeLa, and NIH/3T3 cell lysates
演示 Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide. 应用 应用 Detect PSIP1 using this mouse monoclonal antibody, Anti-PSIP1 Antibody, clone 6E4 validated for use in western blotting, IHC & Immunofluorescence. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunofluorescence Analysis: A 1:200-1,000 dilution from a representative lot detected PSIP1 in NIH/3T3 cells.
Immunohistochemistry Analysis: A 1:1,000 dilution of this antibody detected PSIP1 in rat cerebellum, rat hippocampus, and human cerebellum tissues.
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Purified recombinant fragment of human PSIP1 expressed in E. Coli. 克隆 6E4 宿主 Mouse 同种型 IgG1 品种反应性 RatHumanMonkey 抗体类型 Monoclonal Antibody 基因符号 - PSIP1
纯化方法 Unpurified UniProt编号 - Q05CM9
产品使用声明 质量保证 Evaluated by Western Blotting in HepG2, Jurkat, K562, Cos7, PC-12, HeLa, and NIH/3T3 cell lysates.
Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected PSIP1 in HepG2, Jurkat, K562, Cos7, PC-12, HeLa, and NIH/3T3 cell lysates.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µL
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