• merck millipore,默克密理博,MABN238,Anti-Glucagon Antibody, clone 13D11.33
  • merck millipore,默克密理博,MABN238,Anti-Glucagon Antibody, clone 13D11.33

    产品名称:Anti-Glucagon Antibody, clone 13D11.33
    产品型号:MABN238
    Detect Glucagon using this Anti-Glucagon Antibody, clone 13D11.33 validated for use in IHC(P), Immunofluorescence, ELISA, Multiplexing.

    merck millipore,默克密理博,MABN238,Anti-Glucagon Antibody, clone 13D11.33

  • 产品介绍
  • merck millipore,默克密理博,MABN238,Anti-Glucagon Antibody, clone 13D11.33

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, HELISAMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABN238
    描述 Anti-Glucagon Antibody, clone 13D11.33
    Alternate Names
    • AB932
    • 4030-01F
    • 4031-01F
    背景信息 Glucagon is a hormone that is proteolytically cleaved into at least eight different functional peptides. It is produced by pancreatic cells and it has binding sites in the brain, intestines, and liver, among other tissues. Glucagon is secreted in response to hypoglycemia. Through the combined activation of Gsα- and Gq-coupled transmembrane receptors and their downstream signaling pathways, glucagon stimulates the release of glucose from the liver into the bloodstream. One important mechanism underlying this process is the activation of protein kinase A (PKA). PKA signals result in increased transcription of phosphoenolpyruvate carboxykinase, which encodes the rate-limiting enzyme in the production of glucose from noncarbohydrate substrates. PKA signals may also increase the breakdown of glycogen, and suppress glycolysis. Glucagon may also engage in calcium-dependent signaling via PLC. The importance of glucagon in regulating glucose homeostasis, in conjunction with insulin, is underscored by findings that glucagon and glucagon receptor signaling are disrupted in type II diabetes.
    产品信息
    格式 Purified
    控制
    • Normal rat pancreas tissue
    演示 Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Detect Glucagon using this Anti-Glucagon Antibody, clone 13D11.33 validated for use in IHC(P), Immunofluorescence, ELISA, Multiplexing.
    主要应用
    • ELISA
    应用说明 Immunohistochemistry Analysis: A 1:8,000 dilution from a representative lot detected Glucagon in normal rat pancreas tissue (For enhanced staining results, it is recommended to use a 10,000 dilution of this antibody.).

    ELISA Analysis: A representative lot detected Glucagon in ELISA.

    Luminex® Analysis: A representative lot detected Glucagon in Luminex Assay.
    生物信息
    免疫原品种 Ovalbumin-conjugated linear peptide corresponding to human Glucagon.
    克隆 13D11.33
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG2bκ
    品种反应性 RatHuman
    Species Reactivity Note Demonstrated to react with Human and Rat.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_002045
    基因符号
    • GCG
    纯化方法 Protein G purified
    UniProt编号
    • P01275
    产品使用声明
    质量保证 Evaluated by Immunofluorescence in normal rat pancreas tissue.

    Immunofluorescence Analysis: A 1:8,000 dilution of this antibody detected Glucagon in normal rat pancreas tissue.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABN238,Anti-Glucagon Antibody, clone 13D11.33

上一件merck millipore产品:merck millipore,默克密理博,4610-OP,OmniPur Formamide, Deionized - CAS 75-12-7 - Calbiochem
下一件merck millipore产品:merck millipore,默克密理博,AB13458,Anti-MMP-9 Antibody



whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部