merck millipore,默克密理博,MABN1034,Anti-PPBP Antibody, clone EPR7766, rabbit monoclonal

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merck millipore,默克密理博,MABN1034,Anti-PPBP Antibody, clone EPR7766, rabbit monoclonal
产品名称：Anti-PPBP Antibody, clone EPR7766, rabbit monoclonal
产品型号：MABN1034
Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target. Detect Platelet basic protein using this rabbit mono More>>

merck millipore,默克密理博,MABN1034,Anti-PPBP Antibody, clone EPR7766, rabbit monoclonal

产品介绍

merck millipore,默克密理博,MABN1034,Anti-PPBP Antibody, clone EPR7766, rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABN1034
描述	Anti-PPBP Antibody, clone EPR7766, rabbit monoclonal
Alternate Names	PPBP Platelet basic protein PBP C-X-C motif chemokine 7 Leukocyte-derived growth factor LDGF Macrophage-derived growth factor MDGF Small-inducible cytokine B7
背景信息	Platelet basic protein (PBP) or alternatively named C-X-C motif chemokine 7, Leukocyte-derived growth factor (LDGF), Macrophage-derived growth factor (MDGF), Small-inducible cytokine B7 is encoded by the human gene named PPBP with several synonyms, CTAP3, CXCL7, SCYB7, TGB1 and THBGB1. PPBP is a precursor chemokine molecule that gets processed in to a myriad of secreted bioactive peptides. CTAP-III (Connective tissue activating peptide III --also known as LA-PF4 (Low affinity platelet factor IV), TC-1 (Thrombocidin 1), TC-2 (Thrombocidin 2), Connective tissue activating peptide III 1-81 (CTAP-III(1-81), Beta-thromboglobulin (Beta-TG), Neutrophil-activating peptide 2 (NAP-2), Neutrophil-activating peptide 2(74) (NAP-2(74), Neutrophil-activating peptide 2(73) (NAP-2(73), Neutrophil-activating peptide 2(1-66) (NAP-2(1-66), and Neutrophil-activating peptide 2 (1-63) (NAP-2(1-63). These various bioactive peptides have multiple functions in different cells and tissues. CTAP-III stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for the chemokine receptor CXCR1 and CXCR2 (Interleukin 8 receptor alpha) and can induce proliferation; NAP-2’s various sub peptides like NAP-2(73) are all stimulants for neutrophils, and TC-1 and TC-2 have anti-bacterial properties and can be released from activated platelets. Because of its many influences, levels of PPBP (CXCL7) are being studied as possible biomarkers for everything from monitoring the progression of cancers to combating bacterial and pathogen infections. EMD-Millipore’s Anti-PPBP rabbit monoclonal antibody has been tested in western blot on human platelet lysates.

产品信息
格式	Unpurified
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target. Detect Platelet basic protein using this rabbit monoclonal antibody, Anti-PPBP Antibody & clone EPR7766 validated for use in western blotting.
主要应用	Western Blotting

生物信息
免疫原品种	Synthetic peptide corresponding to human PPBP.
克隆	EPR7766
宿主	Rabbit
品种反应性	Human
抗体类型	Monoclonal Antibody
基因符号	THBGB1 PPBP CTAP3 CXCL7 SCYB7 TGB1
纯化方法	Unpurified
UniProt编号	P02775

产品使用声明
质量保证	Evaluated by Western Blotting in human platelet tissue lysate. Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected PPBP in human platelet tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.