- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN470 描述 Anti-EPAC1 Antibody Alternate Names - EPAC1
- Rap guanine nuclear exchange factor 3
- RAPGEF3
- cAMPGEF-I
- bcm910
- cAMP-GEFI
- Exchange factor directly activated by cAMP
- cAMP-regulated guanine nucleotide exchange factor I
背景信息 Exchange protein directly activated by cAMP 1 (EPAC1) is also known as Rap guanine nuclear exchange factor 3 and cAMPGEF-I. EPAC1 is a guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases which are activated through cAMP binding. EPAC1 couples cAMP production to the activation of the Ras family GTPase, Rap. Activation of Rap drives several cellular processes such as integrin-mediated cell adhesion, vascular endothelial barrier formation, and cardiac myocyte gap junction formation. EPAC1 is part of a signaling complex in which it activates the PI3K gamma complex, which is involved in angiogenesis. EPAC1 may also regulate ion channel formation, intracellular Ca++ signaling, ion transporter activity, and exocytosis. EPAC1 is widely expressed, especially in brain, heart, kidney, pancreas, spleen, ovary, thyroid and spinal cord. 产品信息 格式 Affinity Purified 控制 - Rat skeletal muscle tissue lysate
演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-EPAC1 Antibody is a highly specific rabbit polyclonal antibody, that targets Epac & has been tested in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected EPAC1 in human kidney, thalamus, and cerebellum tissues. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human EPAC1. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 RatHuman 抗体类型 Polyclonal Antibody 基因符号 - EPAC
- EPAC1
- RAPGEF3
- CGEF1
纯化方法 Antigen Affinity purified UniProt编号 - O95398
产品使用声明 质量保证 Evaluated by Western Blotting in rat skeletal muscle tissue lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected EPAC1 in 15 µg of rat skeletal muscle tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,43-041,MILLIPLEX MAP Assay Buffer 2 - Lysates/Reagents for Multiplexing
下一件merck millipore产品：merck millipore,默克密理博,204873,Complement C1, Human
相关产品
merck millipore,默克密理博,71530,T7 Tail Fiber Monoclonal Antibody
merck millipore,默克密理博,373260,Heat Shock Protein Inhibitor I - CAS 218924-25-5 - Calbiochem
merck millipore,默克密理博,DP02A,Anti-SV40 T Antigen (Ab-2) Mouse mAb (PAb416) Agarose Conjugate
merck millipore,默克密理博,43-041,MILLIPLEX MAP Assay Buffer 2 - Lysates/Reagents for Multiplexing
merck millipore,默克密理博,204873,Complement C1, Human
merck millipore,默克密理博,4610-OP,OmniPur Formamide, Deionized - CAS 75-12-7 - Calbiochem
merck millipore,默克密理博,MABN238,Anti-Glucagon Antibody, clone 13D11.33
merck millipore,默克密理博,AB13458,Anti-MMP-9 Antibody
merck millipore,默克密理博,AB5668P,Anti-Neurite Outgrowth Inhibitor B Antibody