merck millipore,默克密理愽
  • merck millipore,默克密理博,MABF527,Anti-CD11c Antibody (mouse), APC-Cy7, clone N418

  • merck millipore,默克密理博,MABF527,Anti-CD11c Antibody (mouse), APC-Cy7, clone N418

    产品名称：Anti-CD11c Antibody (mouse), APC-Cy7, clone N418
    产品型号：MABF527
    This armenian hamster monoclonal antibody Anti-CD11c (mouse), APC-Cy7, clone N418 validated for use in IP, IHC, Immunofluorescence & Flow Cytometry for the detection of CD11c.

    merck millipore,默克密理博,MABF527,Anti-CD11c Antibody (mouse), APC-Cy7, clone N418

  • 产品介绍
  • merck millipore,默克密理博,MABF527,Anti-CD11c Antibody (mouse), APC-Cy7, clone N418

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    MFC, IHCAHmAPC-Cy7Monoclonal Antibody
    描述
    产品目录编号 MABF527
    描述 Anti-CD11c Antibody (mouse), APC-Cy7, clone N418
    Alternate Names
    • CD11c
    • Integrin alpha-X
    • CD11 antigen-like family member C
    • Leukocyte adhesion glycoprotein p150,95 alpha chain
    • Leukocyte adhesion receptor p150,95
    背景信息 The N418 antibody reacts with mouse CD11c, also known as integrin alpha X. This 150 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha X (CD11c) assembles with Integrin beta-2 (CD18) into a receptor complex known as CR4 which can bind and induce signaling through ICAMs and VCAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.The N418 antibody is widely used as a marker for CD11c expression on dendritic cells (DC), often in parallel with markers for CD11b, for identification of developmental stages and mature subsets of this cell type. CD11c is prominently expressed on tissue macrophages, and is also detected on some types of activated T cells and intestinal intraepithelial lymphocytes (IEL).
    产品信息
    格式 APC-Cy7
    演示 Purified Armenian Hamster Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide.
    应用
    应用 This armenian hamster monoclonal antibody Anti-CD11c (mouse), APC-Cy7, clone N418 validated for use in IP, IHC, Immunofluorescence & Flow Cytometry for the detection of CD11c.
    主要应用
    • Flow Cytometry
    • Immunohistochemistry
    生物信息
    免疫原品种 Immunogen information for this antibody is proprietary information.
    克隆 N418
    浓缩 0.2 mg/mL
    宿主 Armenian Hamster
    同种型 IgG
    品种反应性 Mouse
    抗体类型 Monoclonal Antibody
    基因符号
    • Itgax
    纯化方法 Size Exclusion Chromatography
    UniProt编号
    • Q9QXH4
    产品使用声明
    质量保证 The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

    Flow Cytometry Analysis: 0.25 μg of this antibody detected CD11c in one million C57Bl/6 splenocytes.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
    包装信息
    数量 25 µg

    merck millipore,默克密理博,MABF527,Anti-CD11c Antibody (mouse), APC-Cy7, clone N418

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