merck millipore,默克密理博,ABC383,Anti-ADH5 Antibody

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merck millipore,默克密理博,ABC383,Anti-ADH5 Antibody
产品名称：Anti-ADH5 Antibody
产品型号：ABC383
Anti-ADH5 Antibody is a highly specific rabbit polyclonal antibody, that targets Alcohol Dehydrogenase & has been tested in western blotting & IHC.

merck millipore,默克密理博,ABC383,Anti-ADH5 Antibody

产品介绍

merck millipore,默克密理博,ABC383,Anti-ADH5 Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H, M	IHC, WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	ABC383
描述	Anti-ADH5 Antibody
Alternate Names	ADH5 Alcohol dehydrogenase class-3 Alcohol dehydrogenase 5 Alcohol dehydrogenase class chi chain Alcohol dehydrogenase class-III Glutathione-dependent formaldehyde dehydrogenase FALDH FDH GSH-FDH S-(hydroxymethyl)glutathione dehydrogenase
背景信息	Humans express at least seven alcohol dehydrogenase (ADH) isoforms that are encoded by ADH gene cluster (ADH7-ADH1C-ADH1B-ADH1A-ADH6-ADH4-ADH5) at chromosome 4. ADH5 or alcohol dehydrogenase 5, or alternatively alcohol dehydrogenase class-3, Alcohol dehydrogenase class chi chain, Alcohol dehydrogenase class-III, Glutathione-dependent formaldehyde dehydrogenase, (FALDH, FDH, GSH-FDH, GSNOR), and S-(hydroxymethyl) glutathione dehydrogenase and encoded by the human gene named ADH5, ADHX, FDH is a cytoplasmic localized enzyme that catalyzes the oxidation of long-chain primary alcohols as well as S-hydroxymethyl glutathione to release either NADH or NADPH coenzymes. ADH5 is also an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. Formaldehyde can also damage DNA, thus its elimination is doubly important and is essential in cells deficient in the Fanconi anemia DNA repair pathway, though the expression of ADH5 appears to be insensitive to direct exposure to formaldehyde at least at the level of peripheral blood cells. EMD-Millipore’s Anti-ADH5 rabbit polyclonal antibody has been tested in western blot on mouse kidney lysates and in paraffin embedded immunohistochemistry on human prostate cancer tissue sections.

产品信息
格式	Affinity Purified
演示	Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol.

应用
应用	Anti-ADH5 Antibody is a highly specific rabbit polyclonal antibody, that targets Alcohol Dehydrogenase & has been tested in western blotting & IHC.
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected ADH5 in human prostate cancer tissue.

生物信息
免疫原品种	GST-tagged fusion protein corresponding to human ADH5.
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
品种反应性	HumanMouse
抗体类型	Polyclonal Antibody
基因符号	FDH ADH5 ADHX
纯化方法	Antigen Affinity purified
UniProt编号	P11766

产品使用声明
质量保证	Evaluated by Western Blotting in mouse kidney tissue lysate. Western Blotting Analysis: A 1:800 dilution of this antibody detected ADH5 in mouse kidney tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.