merck millipore,默克密理愽
  • merck millipore,默克密理博,MABF187,Anti-KARS Antibody, clone 8G12C1

  • merck millipore,默克密理博,MABF187,Anti-KARS Antibody, clone 8G12C1

    产品名称：Anti-KARS Antibody, clone 8G12C1
    产品型号：MABF187
    Anti-KARS Antibody, clone 8G12C1 is a highly specific mouse monoclonal antibody, that targets Lysyl-tRNA synthetase & has been tested in western blotting & IHC.

    merck millipore,默克密理博,MABF187,Anti-KARS Antibody, clone 8G12C1

  • 产品介绍
  • merck millipore,默克密理博,MABF187,Anti-KARS Antibody, clone 8G12C1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, WBMAscitesMonoclonal Antibody
    描述
    产品目录编号 MABF187
    描述 Anti-KARS Antibody, clone 8G12C1
    Alternate Names
    • LysRS
    • Lysine-tRNA ligase
    • Lysyl-tRNA synthetase
    背景信息 KARS, also known as Lysyl-tRNA synthetase (LysRS), is the enzyme that connects the lysine to its specific tRNA for use in protein translation. KARS is also a powerful inflammatory agent when released into extracellular matrix as one might expect. KARS is largely cytoplasmically localized or localized to internal membranes but isoforms are found in the mitochondria and nucleus as well. KARS became the focus of much attention with HIV-1 as KARS interacted with HIV-1’s GAG protein and facilitated the selective packaging of tRNA3(lys) nucleic acid which acted as the primer for viral reverse transcription and initiation of viral gene expression. There is also at least one genetic disease linked to KARS. It is the cause of Charcot-Marie-Tooth neuropathy a progressive peripheral nervous system disease characterized by progressive weakness and atrophy of the muscles and demyelination and deterioration the peripheral nerves and axons. EMD-Millipore’s Anti-KARS mouse monoclonal antibody has been tested in western blot on recombinant protein and in paraffin embedded immunohistochemistry on human cervical carcinoma tissue sections.
    产品信息
    格式 Ascites
    控制
    • Truncated Trx-KARS recombinant protein, truncated MBP-KARS and full length KARS transfected CHO-K1 cell lysates
    演示 Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
    应用
    应用 Anti-KARS Antibody, clone 8G12C1 is a highly specific mouse monoclonal antibody, that targets Lysyl-tRNA synthetase & has been tested in western blotting & IHC.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected KARS in human cervical carcinoma and human tonsil tissues.

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Purified recombinant fragment of human KARS expressed in E. Coli.
    克隆 8G12C1
    宿主 Mouse
    同种型 IgG1
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    基因符号
    • KIAA0070
    • KRS
    • KARS2
    纯化方法 Unpurified
    UniProt编号
    • Q15046
    产品使用声明
    质量保证 Evaluated by Western Blotting in truncated Trx-KARS recombinant protein, truncated MBP-KARS and full length KARS transfected CHO-K1 cell lysates.

    Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected KARS in truncated Trx-KARS recombinant protein, truncated MBP-KARS and full length KARS transfected CHO-K1 cell lysates.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20°C from date of receipt.
    Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MABF187,Anti-KARS Antibody, clone 8G12C1

上一件merck millipore产品：merck millipore,默克密理博,DR1126,Anti-WARS Mouse mAb (3A12)
下一件merck millipore产品：merck millipore,默克密理博,14-734,FGFR1 (V561M) Protein, active, 10 µg


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