merck millipore,默克密理愽
  • merck millipore,默克密理博,481412,NF-kB Activation Inhibitor IV - CAS 139141-12-1 - Calbiochem

  • merck millipore,默克密理博,481412,NF-kB Activation Inhibitor IV - CAS 139141-12-1 - Calbiochem

    产品名称：NF-kB Activation Inhibitor IV - CAS 139141-12-1 - Calbiochem
    产品型号：481412
    The NF-kB Activation Inhibitor IV, also referenced under CAS 139141-12-1, controls the biological activity of NF-kB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applica More>>

    merck millipore,默克密理博,481412,NF-kB Activation Inhibitor IV - CAS 139141-12-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,481412,NF-kB Activation Inhibitor IV - CAS 139141-12-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₅H₁₃FO139141-12-1
    描述
    概述 A cell-permeable trans-stilbene Resveratrol (Cat. No. 554325) analog that exhibits much enhanced anti-inflammatory potency, but no anti-oxidant activity. Suppresses LPS-induced COX-2 mRNA expression in BV-2 cells (~46% inhibition at 150 nM) and Shown to be ~130-fold more potent than Resveratrol in inhibiting TNF-α-stimulated NF-κB reporter activity in 293T cells (IC50 = 150 nM).
    产品目录编号 481412
    品牌系列 Calbiochem®
    同义词 (E)-2-Fluoro-4ʹ-methoxystilbene
    参考
    参考 Heynekamp, J.J., et al. 2006. J. Med. Chem. 49, 7182.
    产品信息
    CAS号 139141-12-1
    具有ATP竞争性 N
    形式 Crystalline solid
    Hill配方 C₁₅H₁₃FO
    化学配方 C₁₅H₁₃FO
    Molar Mass 228.3
    可逆 N
    结构配方图像
    生物信息
    主靶 NF-κB Activation
    主靶IC50 150 nM inhibiting TNF-α-stimulated NF-κB reporter activity in 293T cells.
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,481412,NF-kB Activation Inhibitor IV - CAS 139141-12-1 - Calbiochem

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