merck millipore,默克密理博,220467,2-Chloro-2ʹ-deoxyadenosine - CAS 4291-63-8

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Merck Millipore 默克密理愽

merck millipore,默克密理博,220467,2-Chloro-2ʹ-deoxyadenosine - CAS 4291-63-8 - Calbiochem

经验配方	CAS号
C₁₀H₁₂ClN₅O₃	4291-63-8

描述
概述	A deoxyadenosine analog that displays strong antileukemic and immunosuppressive activity. Also induces apoptosis in chronic lymphocytic leukemia (CLL) cells.
产品目录编号	220467
品牌系列	Calbiochem®
同义词	2CdA, Cladribine

参考
参考	Bellosillo, B., et al. 1997. Blood 89, 3378; Bryson, H.M., and Sorkin, E.M. 1993. Drugs 46, 872. Robertson, L.E., et al. 1993. Blood 81, 143. Carson, D.A., et al. 1988. Adv. Enzyme Regul. 27, 395. Carson, D.A., et al. 1984. Proc. Natl. Acad. Sci. USA 81, 2232.

生物信息
主靶	Antileukemic and immunosuppressive activity
纯度	≥95% by HPLC

理化信息
细胞可渗透	N
溶解度	DMSO

GHS安全信息
RTECS	AU7357560

安全信息
R相	R: 20/21/22-36/37/38-40 Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Limited evidence of a carcinogenic effect.
S相	S: 22-24/25-26-36/37/39-45 Do not breathe dust. Avoid contact with skin and eyes. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Harmful & Carcinogenic / Teratogenic
储存	+2°C to +8°C
无需冷冻	No
特殊指南	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

merck millipore,默克密理博,220467,2-Chloro-2ʹ-deoxyadenosine - CAS 4291-63-8 - Calbiochem

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