merck millipore,默克密理愽
  • merck millipore,默克密理博,14-871,UbcH5b Protein, recombinant, 100 µg

  • merck millipore,默克密理博,14-871,UbcH5b Protein, recombinant, 100 µg

    产品名称：UbcH5b Protein, recombinant, 100 µg
    产品型号：14-871
    Recombinant fusion protein containing human UbcH5b with an N-terminal His-tag, expressed in E. coli. For use in Activity Assays.

    merck millipore,默克密理博,14-871,UbcH5b Protein, recombinant, 100 µg

  • 产品介绍
  • merck millipore,默克密理博,14-871,UbcH5b Protein, recombinant, 100 µg

    重要规格表

    主要应用 Entrez基因编号 品种 Uni Prot编号
    ACTNM_181838.1, NM_003339.2HumanP62837
    描述
    产品目录编号 14-871
    品牌系列 Upstate
    商名
    • Upstate
    描述 UbcH5b Protein, recombinant, 100 µg
    概述 Recombinant fusion protein containing human UbcH5b with an N-terminal His-tag, expressed in E. coli.
    产品信息
    演示 100 µg recombinant UbcH5b in 100 µL of 50mM Tris-HCl, pH 7.5, 270mM Sucrose, 150mM NaCl, 0.1mM EGTA, 0.1% 2-mercaptoethanol, 0.02% Brij-35, 0.2mM PMSF, and 1mM Benzamidine. Frozen solution.
    应用
    应用 Recombinant fusion protein containing human UbcH5b with an N-terminal His-tag, expressed in E. coli. For use in Activity Assays.
    主要应用
    • Activity Assay
    生物信息
    纯度 ~85% by SDS PAGE and Coomassie blue staining.
    来源 Expressed in E. coli.
    品种 Human
    Entrez基因编号
    • NM_181838.1
    • NM_003339.2
    Entrez基因汇总 The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
    基因符号
    • UBC4
    • UBE2D2
    • UBCH5B
    • PUBC1
    • E2
    • UbcH5B
    • UBC4/5
    • E2(17)KB2
    纯化方法 ProBond Resin chromatography
    UniProt编号
    • P62837
    UniProt汇总 FUNCTION: SwissProt: P62837 # Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53.
    SIZE: 147 amino acids; 16735 Da
    SUBUNIT: Interacts with SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex.
    SIMILARITY: SwissProt: P62837 ## Belongs to the ubiquitin-conjugating enzyme family.
    产品使用声明
    质量保证 Routinely evaluated by ubiquitin assay
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 2 years at -70°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,14-871,UbcH5b Protein, recombinant, 100 µg

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