merck millipore,默克密理愽
  • merck millipore,默克密理博,MABF111,Anti-MIF Antibody, clone M1, preservative free

  • merck millipore,默克密理博,MABF111,Anti-MIF Antibody, clone M1, preservative free

    产品名称：Anti-MIF Antibody, clone M1, preservative free
    产品型号：MABF111
    This Anti-MIF Antibody, clone M1, preservative free is validated for use in flow cytometry, neutralizing & western blotting for the detection of MIF.

    merck millipore,默克密理博,MABF111,Anti-MIF Antibody, clone M1, preservative free

  • 产品介绍
  • merck millipore,默克密理博,MABF111,Anti-MIF Antibody, clone M1, preservative free

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWB, FCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABF111
    描述 Anti-MIF Antibody, clone M1, preservative free
    Alternate Names
    • Phenylpyruvate tautomerase
    • Macrophage migration inhibitory factor
    • MIF
    • Glycosylation-inhibiting factor
    • GIF
    • L-dopachrome isomerase
    • L-dopachrome tautomerase
    背景信息 MIF, also known as Macrophage migration inhibitory factor, or Glycosylation-inhibiting factor (GIF), L-dopachrome isomerase, L-dopachrome tautomerase, or Phenylpyruvate tautomerase, and encoded by the gene MIF/GLIF/MMIF, is proinflammatory cytokine involved in the innate immune response to bacterial pathogens. MIF is secreted by macrophages upon stimulation by bacterial lipopolysaccharide or bacterial antigens, and the expression of MIF at sites of inflammation suggests a role as a mediator in regulating the function of macrophages in host defense. MIF also counteracts the anti-inflammatory activity of glucocorticoids and has various enzyme activities but their physiological function is not known. MIF expression is primarily lymphocytes, macrophages and immune system cells. Defects in MIF may be associated with Rheumatoid arthritis systemic juvenile disease, an inflammatory articular disorder with systemic onset beginning at age 16. Also serum levels of MIF are elevated in cases of severe sepsis and are correlated with low survival.
    产品信息
    格式 Purified
    演示 Purified mouse monoclonal IgG1κ in buffer containing PBS without preservatives.
    应用
    应用 This Anti-MIF Antibody, clone M1, preservative free is validated for use in flow cytometry, neutralizing & western blotting for the detection of MIF.
    主要应用
    • Western Blotting
    • Flow Cytometry
    应用说明 Neutralization Assay Analysis: A representative lot from an independent laboratory detected MIF during the migration of human peripheral blood granulocytes (Rupreht, R. R., et al. (2000). Pflugers Arch. 440(5 Suppl):R78-80.).
    生物信息
    免疫原品种 Recombinant protein corresponding to human MIF.
    克隆 M1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG1κ
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_002406
    基因符号
    • MMIF
    • MIF
    • GLIF
    纯化方法 Protein G purified
    UniProt编号
    • P14174
    产品使用声明
    质量保证 Evaluated by Flow Cytometry by Jurkat cells.

    Flow Cytometry: 1 µg of this antibody detected MIF in 1X10E6 Jurkat cells.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20°C from date of receipt.
    Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABF111,Anti-MIF Antibody, clone M1, preservative free

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