merck millipore,默克密理愽
  • merck millipore,默克密理博,288500,DL-α-Difluoromethylornithine, Hydrochloride - CAS 96020-91-6 - Calbiochem

  • merck millipore,默克密理博,288500,DL-α-Difluoromethylornithine, Hydrochloride - CAS 96020-91-6 - Calbiochem

    产品名称：DL-α-Difluoromethylornithine, Hydrochloride - CAS 96020-91-6 - Calbiochem
    产品型号：288500
    A cell-permeable, anticancer agent that acts as a specific and irreversible inhibitor of ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine biosynthesis.

    merck millipore,默克密理博,288500,DL-α-Difluoromethylornithine, Hydrochloride - CAS 96020-91-6 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,288500,DL-α-Difluoromethylornithine, Hydrochloride - CAS 96020-91-6 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₆H₁₂F₂N₂O₂ · HCl · H₂O96020-91-6
    描述
    概述 A cell-permeable, anticancer agent that acts as a specific and irreversible inhibitor of ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine biosynthesis. Inhibits B16 melanoma-induced angiogenesis in ovo and proliferation of vascular endothelial cells in vitro.
    产品目录编号 288500
    品牌系列 Calbiochem®
    同义词 DFMO, Eflornithine, RMI-71782
    参考
    参考 Meyskens, F.L., Jr., and Gerner, E.W. 1995. J. Cell. Biochem. (Suppl.) 22, 126.
    Feuerstein, B.G., et al. 1992. Cancer Res. 52, 6782.
    Takigawa, M., et al. 1990. Cancer Res. 50, 4131.
    Weeks, C.E., et al. 1982. Proc. Natl. Acad. Sci. USA 79, 6028.
    Danzin, C., et al. 1979. Life Sci. 24, 519.
    产品信息
    CAS号 96020-91-6
    具有ATP竞争性 N
    形式 White powder
    Hill配方 C₆H₁₂F₂N₂O₂ · HCl · H₂O
    化学配方 C₆H₁₂F₂N₂O₂ · HCl · H₂O
    Molar Mass 236.7
    吸湿 Hygroscopic
    可逆 N
    结构配方图像
    生物信息
    主靶 ODC
    纯度 ≥99% by TLC
    理化信息
    细胞可渗透 Y
    溶解度 MeOH or H₂O
    GHS安全信息
    RTECS RM2981900
    安全信息
    R相 R: 40

    Limited evidence of a carcinogenic effect.
    S相 S: 22-36

    Do not breathe dust.
    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Carcinogenic / Teratogenic
    储存 +15°C to +30°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

    merck millipore,默克密理博,288500,DL-α-Difluoromethylornithine, Hydrochloride - CAS 96020-91-6 - Calbiochem

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