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  • merck millipore,默克密理博,EZHL-80SK,Human Leptin

  • merck millipore,默克密理博,EZHL-80SK,Human Leptin "Dual Range" ELISA

    产品名称：Human Leptin "Dual Range" ELISA
    产品型号：EZHL-80SK
    This Human Leptin "Dual Range" ELISA is used to measure & quantify Leptin levels in Metabolism & Endocrine & Neuroscience research.

    merck millipore,默克密理博,EZHL-80SK,Human Leptin "Dual Range" ELISA

  • 产品介绍
  • merck millipore,默克密理博,EZHL-80SK,Human Leptin "Dual Range" ELISA

    重要规格表

    可用的分析物 品种反应性 主要应用 检测方法
    LeptinHELISAColorimetric, Fluorescent
    描述
    产品目录编号 EZHL-80SK
    描述 Human Leptin "Dual Range" ELISA
    背景信息 Leptin is synthesized in adipocytes as a 16 kDa molecule and the circulating level is directly proportional to the total amount of fat in the body.
    产品信息
    检测方法 ColorimetricFluorescent
    精度（%）
    • Intra-assay: 2.6–4.6 Sensitive Assay 1.4–4.9
    • Inter-assay: 2.6–6.2 Sensitive Assay 1.3–8.6
    应用
    应用 This Human Leptin "Dual Range" ELISA is used to measure & quantify Leptin levels in Metabolism & Endocrine & Neuroscience research.
    主要应用
    • ELISA
    应用说明 Room temperature, 3.5 hour assay 25 μL sample size (Sensitive Assay: 50μL)
    生物信息
    品种反应性 Human
    可用的分析物
    • Leptin
    Entrez基因编号
    • NM_000230.1
    Entrez基因汇总 This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
    基因符号
    • OBS
    • LEP
    • leptin
    • OB
    • obesity
    UniProt编号
    • P41159
    UniProt汇总 FUNCTION: SwissProt: P41159 # May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
    SIZE: 167 amino acids; 18641 Da
    SUBUNIT: Interacts with SIGLEC6.
    SUBCELLULAR LOCATION: Secreted.
    DISEASE:SwissProt: P41159 # Defects in LEP may be a cause of autosomal recessive obesity [MIM:601665].
    SIMILARITY: SwissProt: P41159 ## Belongs to the leptin family.
    准确度
    • Sensitive Assay 86–102%
    • 94–114%
    理化信息
    灵敏度
    • 0.5 ng/mL
    • Sensitive Assay 0.125 ng/mL
    稀释的线性 Sensitive Assay 96–125%80–105%
    标准曲线范围
    • Sensitive Assay 0.125–20 ng/mL
    • 0.5–100 ng/mL
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    包装信息
    数量 96-well strip plate

    merck millipore,默克密理博,EZHL-80SK,Human Leptin "Dual Range" ELISA

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