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品种反应性 主要应用 宿主 格式 抗体类型 H WB R Purified Monoclonal Antibody 描述 产品目录编号 MABE369 描述 Anti-Suv4–20h2 Antibody, clone 6B9 Alternate Names - Suv4-20h2
- Histone-lysine N-methyltransferase SUV420H2
- Lysine N-methyltransferase 5C
- Suppressor of variegation 4-20 homolog 2
- Su(var)4-20 homolog 2
背景信息 Suppressor of variegation 4-20 homolog 2 (Suv4-20h2), also known as Lysine N-methyltransferase 5C (KMT5C), is a Histone-lysine N-methyltransferase that specifically trimethylates Lys-20 of histone H4. Suv4-20h2 mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. In mammals, Histone H4 Lys-20 trimethylation (H4K20me3) is one of the most common chromatin modifications and it has been implicated in various biological processes, including heterochromatin formation, telomere function, imprinting, X inactivation, DNA damage repair and cancer progression. 产品信息 格式 Purified 控制 - H9 human embryonic stem cell lysate
演示 Purified rat monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect the Suv4–20h2 protein using this Anti-Suv4–20h2, clone 6B9 validated for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human Suv4-20h2. 克隆 6B9 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rat 同种型 IgG2bκ 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_116090
基因符号 - PP7130
- SUV420H2
- KMT5C
纯化方法 Protein G purified UniProt编号 - Q86Y97
产品使用声明 质量保证 Evaluated by Western Blot in H9 human embryonic stem cell lysate.
Western Blot Analysis: 4.0 µg/mL of this antibody detected Suv4-20h2 in 10 µg of H9 human embryonic stem cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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