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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB3854 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-UbcH1 Antibody Alternate Names - E2 Ubiquitin-conjugating Enzyme
- E2-25K
背景信息 Unique among ubiquitin conjugating enzymes, E2-25K (UbcH2) catalyses the synthesis of poly-Ub chains linked via K48-G76 isopeptide bonds in vitro. It has been observed to form cyclic polyubiquitin and to add NEDD8 to poly-Ub chains. E2-25K functions only with mammalian E1. 产品信息 格式 Affinity Purified 演示 Protein A purified immunoglobulin in liquid PBS, pH 7.4, with 20% glycerol. 应用 应用 Detect UbcH1 using this Anti-UbcH1 Antibody validated for use in WB. 主要应用 - Western Blotting
应用说明 Western blot: 1:100-1:1000
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Full length, highly purified, UbcH1 protein. 宿主 Rabbit 特异性 Recognizes UbcH1 (E2-25K). 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_182666.1
- NM_003341.3
Entrez基因汇总 The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. 基因符号 - EC 6.3.2.19
- UBE2E1
- UbcH6
- UBCH6
UniProt编号 - P51965
UniProt汇总 FUNCTION: SwissProt: P51965 # Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins.
SIZE: 193 amino acids; 21404 Da
SUBUNIT: Interacts with RNF14.
SIMILARITY: SwissProt: P51965 ## Belongs to the ubiquitin-conjugating enzyme family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -70°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. May be stored at 2-8°C for up to 1 month. 包装信息 数量 200 µL
上一件merck millipore产品：merck millipore,默克密理博,204879,Complement C1s, Human, Activated, Two-Chain Form
下一件merck millipore产品：merck millipore,默克密理博,324725,Endoglycosidase F1, Elizabethkingia meningosepticum, Recombinant, E. coli
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