- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
-
-
merck millipore,默克密理博,MABE159,Anti-Fox1 Antibody, clone D8F8
产品名称：Anti-Fox1 Antibody, clone D8F8
产品型号：MABE159
Anti-Fox1 Antibody, clone D8F8 is a Mouse Monoclonal Antibody for detection of Fox1 also known as hexaribonucleotide binding protein 1, Ataxin-2-binding protein 1 & has been validated in WB.
merck millipore,默克密理博,MABE159,Anti-Fox1 Antibody, clone D8F8
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M WB M Purified Monoclonal Antibody 描述 产品目录编号 MABE159 描述 Anti-Fox1 Antibody, clone D8F8 Alternate Names - fox-1 homolog A
- hexaribonucleotide binding protein 1
- Ataxin-2-binding protein 1
- ataxin 2-binding protein 1
- Hexaribonucleotide-binding protein 1
背景信息 Fox1, also commonly referred to as Ataxin-2-binding protein 1, is an RNA binding protein involved in the regulation of tissue-specific alternative splicing. This protein contains a highly conserved RRM (RNA recognition motif) and associates with 5'-UGCAUGU-3' elements. This protein has been demonstrated to regulate alternative splicing of tissue specific exons and differentially spliced exons during erythropoiesis. Its alternative name, Ataxin-2-binding protein, is a result of its association with the C terminus of ataxin 2 which may contribute to the pathology of the neurogenerative disease spinocerebellar ataxia type 2 (SCA2). 产品信息 格式 Purified 控制 - Mouse heart tissue lysate
演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-Fox1 Antibody, clone D8F8 is a Mouse Monoclonal Antibody for detection of Fox1 also known as hexaribonucleotide binding protein 1, Ataxin-2-binding protein 1 & has been validated in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 Recombinant protein corresponding to mouse Fox1. 克隆 D8F8 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 Mouse Species Reactivity Note Demonstrated to react with mouse. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_067452
基因符号 - A2BP
- FOX1
- A2BP1
纯化方法 Protein G UniProt编号 - Q9JJ43
UniProt汇总 FUNCTION: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis.
SUBUNIT STRUCTURE: Binds to the C-terminal of ATXN2.
SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Note: Predominantly nuclear.
TISSUE SPECIFICTY: Detected in brain (at protein level). Detected in heart, brain, neurons, skeletal muscle and embryo.
SEQUENCE SIMILARITIES: Contains 1 RRM (RNA recognition motif) domain.产品使用声明 质量保证 Evaluated by Western Blot in mouse heart tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Fox1 on 10 µg of mouse heart tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,05-904,Anti-HA Tag Antibody
下一件merck millipore产品：merck millipore,默克密理博,AB2242,Anti-SUR1/2 Antibody
相关产品
merck millipore,默克密理博,CBL66,Anti-Atrial Natriuretic Peptide Antibody, clone 23/1
merck millipore,默克密理博,ABC324,Anti-PDL-1 Antibody
merck millipore,默克密理博,476480,PKC 20-28, Cell-Permeable, Myristoylated - Calbiochem
merck millipore,默克密理博,HTS008RTA,Ready-to-Assay™ CCR3 Chemokine Receptor Frozen Cells
merck millipore,默克密理博,05-904,Anti-HA Tag Antibody
merck millipore,默克密理博,AB2242,Anti-SUR1/2 Antibody
merck millipore,默克密理博,MABC777,Anti-ING1, clone EPR6788, Rabbit Monoclonal Antibody
merck millipore,默克密理博,AB19167,Anti-MMP-2 Antibody, whole molecule
merck millipore,默克密理博,MAB5206,Anti-Amyloid Antibody, β 1-16, clone DE2
merck millipore,默克密理博,04-1071,Anti-SynGAP (CT) Antibody, clone EPR2883Y, rabbit monoclonal