• merck millipore,默克密理博,476480,PKC 20-28, Cell-Permeable, Myristoylated - Calbiochem
  • merck millipore,默克密理博,476480,PKC 20-28, Cell-Permeable, Myristoylated - Calbiochem

    产品名称:PKC 20-28, Cell-Permeable, Myristoylated - Calbiochem
    产品型号:476480
    Pseudosubstrate sequence from protein kinase Cα and β ( PKCα and PKCβ).

    merck millipore,默克密理博,476480,PKC 20-28, Cell-Permeable, Myristoylated - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,476480,PKC 20-28, Cell-Permeable, Myristoylated - Calbiochem

    重要规格表

    经验配方
    C₆₀H₁₀₆N₁₈O₁₁
    描述
    概述 Pseudosubstrate sequence from protein kinase Cα and β ( PKCα and PKCβ). N-Terminus is myristoylated to allow membrane permeability. Highly specific, reversible, and substrate competitive inhibitor of TPA activation of MARCKS phosphorylation in fibroblast primary cultures (IC50 = 8 µM); exhibits 98% inhibition at 100 µM.
    产品目录编号 476480
    品牌系列 Calbiochem®
    同义词 Myr-N-FARKGALRQ-NH₂, Myristoylated Protein Kinase C Inhibitor 20-28, Cell-Permeable, Protein Kinase C 20-28, Cell-Permeable, Myristoylated
    参考
    参考 Eichholtz, T., et al. 1993. J. Biol. Chem. 268, 1982.
    Ward, N.E. and O’Brian, C.A. 1993. Biochemistry 32, 11903.
    产品信息
    具有ATP竞争性 N
    形式 Lyophilized solid
    配方 Supplied as a trifluoroacetate salt.
    Hill配方 C₆₀H₁₀₆N₁₈O₁₁
    化学配方 C₆₀H₁₀₆N₁₈O₁₁
    Molar Mass 1255.6
    吸湿 Hygroscopic
    肽序列 N-Myr-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-NH₂
    可逆 Y
    基于肽含量售出 Yes
    生物信息
    主靶 TPA activation of MARCKS phosphorylation in fibroblast primary cultures
    主靶IC50 8 µM against TPA activation of MARCKS phosphorylation in fibroblast primary cultures
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 Tris-HCl, pH 7.5 or H₂O
    肽含量 Yes
    肽序列 N-Myr-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-NH₂
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

    merck millipore,默克密理博,476480,PKC 20-28, Cell-Permeable, Myristoylated - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,ABC324,Anti-PDL-1 Antibody
下一件merck millipore产品:merck millipore,默克密理博,HTS008RTA,Ready-to-Assay™ CCR3 Chemokine Receptor Frozen Cells



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