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merck millipore,默克密理博,476480,PKC 20-28, Cell-Permeable, Myristoylated - Calbiochem
产品名称:PKC 20-28, Cell-Permeable, Myristoylated - Calbiochem
产品型号:476480
Pseudosubstrate sequence from protein kinase Cα and β ( PKCα and PKCβ).
merck millipore,默克密理博,476480,PKC 20-28, Cell-Permeable, Myristoylated - Calbiochem
- 产品介绍
重要规格表
经验配方 C₆₀H₁₀₆N₁₈O₁₁ 描述 概述 Pseudosubstrate sequence from protein kinase Cα and β ( PKCα and PKCβ). N-Terminus is myristoylated to allow membrane permeability. Highly specific, reversible, and substrate competitive inhibitor of TPA activation of MARCKS phosphorylation in fibroblast primary cultures (IC50 = 8 µM); exhibits 98% inhibition at 100 µM. 产品目录编号 476480 品牌系列 Calbiochem®
同义词 Myr-N-FARKGALRQ-NH₂, Myristoylated Protein Kinase C Inhibitor 20-28, Cell-Permeable, Protein Kinase C 20-28, Cell-Permeable, Myristoylated 参考 参考 Eichholtz, T., et al. 1993. J. Biol. Chem. 268, 1982.
Ward, N.E. and O’Brian, C.A. 1993. Biochemistry 32, 11903.产品信息 具有ATP竞争性 N 形式 Lyophilized solid 配方 Supplied as a trifluoroacetate salt. Hill配方 C₆₀H₁₀₆N₁₈O₁₁ 化学配方 C₆₀H₁₀₆N₁₈O₁₁ Molar Mass 1255.6 吸湿 Hygroscopic
肽序列 N-Myr-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-NH₂ 可逆 Y 基于肽含量售出 Yes
生物信息 主靶 TPA activation of MARCKS phosphorylation in fibroblast primary cultures 主靶IC50 8 µM against TPA activation of MARCKS phosphorylation in fibroblast primary cultures 纯度 ≥95% by HPLC 理化信息 细胞可渗透 Y 溶解度 Tris-HCl, pH 7.5 or H₂O 肽含量 Yes
肽序列 N-Myr-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-NH₂ 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
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