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merck millipore,默克密理博,MABD85,Anti-LIMD1 Antibody, clone 3F2/C6
产品名称：Anti-LIMD1 Antibody, clone 3F2/C6
产品型号：MABD85
Detect LIMD1 using this Anti-LIMD1 Antibody, clone 3F2/C6 validated for use in ICC, IHC, Immunoprecipitation, Western Blotting.
merck millipore,默克密理博,MABD85,Anti-LIMD1 Antibody, clone 3F2/C6
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB, ICC, IHC M Purified Monoclonal Antibody 描述 产品目录编号 MABD85 描述 Anti-LIMD1 Antibody, clone 3F2/C6 Alternate Names - LIM domain-containing protein 1
背景信息 LIMD1 (LIM domains-containing protein 1) is a tumor suppressor and member of the Ajuba family of LIM domain-containing proteins. LIMD1 interacts with retinoblastoma protein (pRB), inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1-responsive elements. Recently, LIMD1 has been implicated in regulating cellular processes involved in hypoxia. LIMD1 acts as a molecular scaffold, simultaneously binding the prolyl hydroxylases (PHDs) and von Hippel Lindau tumor suppressors (VHL), thereby assembling a PHD-LIMD1-VHL protein complex and creating an enzymatic niche that enables efficient degradation of HIF-1α. 产品信息 格式 Purified 控制 - H1299 cell lysates.
演示 Purified mouse monoclonal IgG1κ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect LIMD1 using this Anti-LIMD1 Antibody, clone 3F2/C6 validated for use in ICC, IHC, Immunoprecipitation, Western Blotting. 主要应用 - Western Blotting
- Immunocytochemistry
- Immunohistochemistry
应用说明 This antibody has been shown to work in Immunocytochemical applications (Foxler, D., et al. (2012).
This antibody has been shown to work in Immunohistochemical applications (Sharp, T., et al. (2008).
This antibody has been shown to work in Immunoprecipitation applications (Courtesy of Dr. Tyson Sharp, Cancer Research, UK)生物信息 免疫原品种 Recombinant protein corresponding to human LIMD1 克隆 3F2/C6 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 This antibody recognizes human LIMD1. 同种型 IgG1κ 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_055055
基因符号 - LIMD1
纯化方法 Protein G purified UniProt编号 - Q9UGP4
产品使用声明 质量保证 Evaluated by Western Blot in H1299 cell lysates.
Western Blot Analysis: A 1:2000 dilution of this antibody detected LIMD1 in H1299 cell lysates.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt.
包装信息 数量 100 µL
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