merck millipore,默克密理愽
  • merck millipore,默克密理博,MABC587,Anti-Nucleolin Antibody, clone 364-5-10-5

  • merck millipore,默克密理博,MABC587,Anti-Nucleolin Antibody, clone 364-5-10-5

    产品名称：Anti-Nucleolin Antibody, clone 364-5-10-5
    产品型号：MABC587
    This Anti-Nucleolin Antibody, clone 364-5-10-5 is validated for use in Western Blotting and Immunohistochemistry (Paraffin) and Immunocytochemistry and Flow Cytometry for the detection of Nucleolin.

    merck millipore,默克密理博,MABC587,Anti-Nucleolin Antibody, clone 364-5-10-5

  • 产品介绍
  • merck millipore,默克密理博,MABC587,Anti-Nucleolin Antibody, clone 364-5-10-5

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, HFC, WB, ICCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABC587
    Replaces MABE466
    描述 Anti-Nucleolin Antibody, clone 364-5-10-5
    Alternate Names
    • Protein C23
    • Nucleolin
    背景信息 Nucleolin, also known as C23, is the major nucleolar protein of exponentially growing eukaryotic cells. It is a ubiquitous conserved multi-domain phosphoprotein found in all vertebrate species. Nucleolin contains a specific bipartite nuclear localization signal sequence and three different structural domains. Nucleolin is a multifunctional protein involved in most steps of ribosome biogenesis. Nucleolin has been implicated in chromatin structure, rDNA transcription, rRNA maturation, ribosome assembly, cytokinesis, nucleogenesis, cell proliferation and growth, and
    nucleo-cytoplasmic transport. Nucleolin also exhibits autodegradation, DNA and RNA helicase activities, and DNA-dependent ATPase activity. Nucleolin activities may be regulated by proteolysis, methylation, ADPribosylation, and phosphorylation by several kinases, including casein kinase II (CK2), p34cdc2, and protein kinase C-ζ.
    产品信息
    格式 Purified
    演示 Purified mouse monoclonal IgG1λ in buffer containing PBS without preservatives.
    应用
    应用 This Anti-Nucleolin Antibody, clone 364-5-10-5 is validated for use in Western Blotting and Immunohistochemistry (Paraffin) and Immunocytochemistry and Flow Cytometry for the detection of Nucleolin.
    主要应用
    • Flow Cytometry
    • Western Blotting
    • Immunocytochemistry
    应用说明 Western Blotting Analysis: 1.0 µg/mL from a representative lot detected Nucleolin in 10 µg of NIH/3T3 cell lysate.

    Immunohistochemistry Analysis: A 1:250-1,000 dilution from a representative lot detected Nucleolin in human breast cancer and human kidney tissue.

    Immunohistochemistry Analysis: A 1:10 dilution from a representative lot detected Nucleolin in ovarian cancer metastasis-infiltrated human lymph node tissue.

    Immunocytochemistry Analysis: A 1:250 dilution from a representative lot detected Nucleolin in A431 and HEK293 cells.
    DyLight® is a registered trademark of Thermo Fisher Scientific.

    Flow Cytometry Analysis: A representative lot detected Nucleolin in NK-92MI cells gated and ungated for CD56.
    生物信息
    免疫原品种 Corresponding to human Nucleolin.
    克隆 364-5-10-5
    浓缩 Please refer to lot specific datasheet.
    宿主 Mouse
    同种型 IgG1λ
    品种反应性 MouseHuman
    Species Reactivity Note Human, Mouse.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_005372
    基因符号
    • NCL
    纯化方法 Protein G purified
    UniProt编号
    • P19338
    产品使用声明
    质量保证 Evaluated by Western Blotting in HeLa cell lysate.

    Western Blotting Analysis: 1.0 µg/mL of this antibody detected Nucleolin in 10 µg of HeLa cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20°C from date of receipt.
    Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABC587,Anti-Nucleolin Antibody, clone 364-5-10-5

上一件merck millipore产品：merck millipore,默克密理博,AB9474,Anti-Prostaglandin F2-α Receptor Antibody
下一件merck millipore产品：merck millipore,默克密理博,05-957,Anti-MAP Kinase 1/Erk 1 Antibody, CT, rabbit monoclonal


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