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merck millipore,默克密理博,MABC174,Anti-Smac/Diablo Antibody, clone 3A9.1
产品名称:Anti-Smac/Diablo Antibody, clone 3A9.1
产品型号:MABC174
Detect Smac/DIABLO using this mouse monoclonal antibody, Anti-Smac/Diablo Antibody, clone 3A9.1 validated for use in western blotting & IHC.
merck millipore,默克密理博,MABC174,Anti-Smac/Diablo Antibody, clone 3A9.1
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MABC174 Replaces 04-578 描述 Anti-Smac/Diablo Antibody, clone 3A9.1 Alternate Names - Second mitochondria-derived activator of caspase, Smac
- Diablo homolog, mitochondrial
- Direct IAP-binding protein with low pl
背景信息 Smac/DIABLO (Second Mitochondria-derived Activator of Caspases/Direct IAP Binding Protein with Low PI) is localized to the mitochondria and involved in activating programmed cell death, or apoptosis. In response to apoptotic stimuli, Smac/DIABLO is released from the mitochondria and binds anti-apoptotic IAP proteins, supressing their inhibitory activity and promoting caspase activation. This interaction involves primarily the amino-terminal residues of Smac/DIABLO with the BIR3 region of the IAP protein. 产品信息 格式 Purified 控制 - Human testis tissue lysate
演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect Smac/DIABLO using this mouse monoclonal antibody, Anti-Smac/Diablo Antibody, clone 3A9.1 validated for use in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Western Blotting Analysis: 0.5 µg/mL from a representative lot detected Smac/Diablo in 10 µg of human heart tissue lysate.
Western Blotting Analysis: 0.5 µg/mL from a representative lot detected Smac/Diablo in 10 µg of human kidney tissue lysate.
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Smac/Diablo in human renal tubule tissues, testis tissues, and seminiferous tubule tissues.生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human Smac/Diablo. 克隆 3A9.1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_063940
基因符号 - SMAC
- DIABLO
纯化方法 Protein G purified UniProt编号 - Q9NR28
产品使用声明 质量保证 Evaluated by Western Blotting in human testis tissue lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected Smac/Diablo in 10 µg of human testis tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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