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merck millipore,默克密理博,07-229,Anti-TACC1 Antibody
产品名称：Anti-TACC1 Antibody
产品型号：07-229
Detect TACC1 also known as transforming acidic coiled-coil containing protein 1 with Anti-TACC1 Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in IP & WB.
merck millipore,默克密理博,07-229,Anti-TACC1 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 07-229 品牌系列 Upstate
商名 - Upstate
描述 Anti-TACC1 Antibody 产品信息 格式 Affinity Purified 演示 2M Tris pH 8.0, 1.5M NaCl, 1mM EDTA, 0.05% sodium azide before the addition of glycerol to 30% 应用 应用 Detect TACC1 also known as transforming acidic coiled-coil containing protein 1 with Anti-TACC1 Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in IP & WB. 主要应用 - Western Blotting
生物信息 免疫原品种 peptide corresponding to amino acids 219-235 (CPELVPSRRSKLRKPKP) of human TACC1 宿主 Rabbit 特异性 TACC1 同种型 IgG 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_006283
Entrez基因汇总 The function of this gene has not yet been determined; however, it is speculated that it may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. 基因符号 - KIAA1103
- TACC1
- DKFZp686K18126
- Ga55
纯化方法 Immunoaffinity chromatography UniProt编号 - O75410
UniProt汇总 FUNCTION: SwissProt: O75410 # Likely involved in the processes that promote cell division prior to the formation of differentiated tissues.
SIZE: 805 amino acids; 87794 Da
SUBUNIT: Interacts with KIAA0097/CH-TOG and with the oncogenic transcription factor YEATS4. Interacts with the Aurora kinases A and B (STK6 and AURKB). Interacts with LSM7, TDRD7 and SNRPG. Interacts with GCN5L2 and PCAF.
SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Nucleus during interphase. Weakly concentrated at centrosomes during mitosis.
TISSUE SPECIFICITY: Isoform 1, isoform 3 and isoform 5 are ubiquitous. Isoform 2 is strongly expressed in the brain, weakly detectable in lung and colon, and overexpressed in gastric cancer. Isoform 4 is not detected in normal tissues, but strong expression was found in gastric cancer tissues.
DEVELOPMENTAL STAGE: Expressed at high level during early embryogenesis.
PTM: Isoform 1 is heavily phosphorylated; isoform 6 is not. Phosphorylated upon DNA damage, probably by ATM or ATR.
SIMILARITY: SwissProt: O75410 ## Belongs to the TACC family. & Contains 2 SPAZ (Ser/Pro-rich AZU-1) domains.
MISCELLANEOUS: Down-regulated in a subset of cases of breast cancer.产品使用声明 质量保证 routinely evaluated by immunoblot on RIPA lysates from HeLa cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 1 year at -20°C 包装信息 数量 200 µg
上一件merck millipore产品：merck millipore,默克密理博,F-04-B,Modified Barth's Saline (1X), liquid, without Ficoll™ 400
下一件merck millipore产品：merck millipore,默克密理博,7710-OP,OmniPur Sodium Chloride - CAS 7647-14-5 - Calbiochem
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