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merck millipore,默克密理博,MABC111,Anti-STK3/MST2 Antibody, clone 9G7.1
产品名称:Anti-STK3/MST2 Antibody, clone 9G7.1
产品型号:MABC111
Anti-STK3/MST2 Antibody, clone 9G7.1 detects level of STK3/MST2 & has been published & validated for use in Western Blotting & IHC.
merck millipore,默克密理博,MABC111,Anti-STK3/MST2 Antibody, clone 9G7.1
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H IHC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MABC111 描述 Anti-STK3/MST2 Antibody, clone 9G7.1 Alternate Names - Serine/threonine-protein kinase Krs-1
- Serine/threonine-protein kinase 3
- Mammalian STE20-like protein kinase 2
- MST-2
- STE20-like kinase MST2
背景信息 Mammalian Ste20-like kinase 2 (MST2) is a serine/threonine kinase found in the kidney, placenta, heart, lung, and brain. It regulates organ size, cell proliferation, tumorigenesis, and apoptosis. Under conditions of cell stress, such as oxidative damage, MST2 is cleaved by caspase-3, and is irreversibly autophosphorylated at Thr180. Activated MST2 forms a stable complex with STK3 and triggers a signaling cascade which inhibits the translocation of YAP1 to the nucleus and consequent suppression of YAP1-mediated apoptosis. 产品信息 格式 Purified 控制 - Rat kidney tissue lysate
演示 Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide. 应用 应用 Anti-STK3/MST2 Antibody, clone 9G7.1 detects level of STK3/MST2 & has been published & validated for use in Western Blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected STK3/MST2 in human placenta tissues, normal human kidney tissue and human kidney cancer tissue. 生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human STK3/MST2. 克隆 9G7.1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgMκ 品种反应性 RatHuman Species Reactivity Note Demonstrated to react with Rat and Human. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_006272
基因符号 - MST2
- STK3
- KRS1
纯化方法 Purified by ion-exchange chromatography UniProt编号 - Q13188
产品使用声明 质量保证 Evaluated by Western Blot in rat kidney tissue lysate.
Western Blot Analysis: 0.25 µg/mL of this antibody detected STK3/MST2 in 10 µg of rat kidney tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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