• merck millipore,默克密理博,MABC111,Anti-STK3/MST2 Antibody, clone 9G7.1
  • merck millipore,默克密理博,MABC111,Anti-STK3/MST2 Antibody, clone 9G7.1

    产品名称:Anti-STK3/MST2 Antibody, clone 9G7.1
    产品型号:MABC111
    Anti-STK3/MST2 Antibody, clone 9G7.1 detects level of STK3/MST2 & has been published & validated for use in Western Blotting & IHC.

    merck millipore,默克密理博,MABC111,Anti-STK3/MST2 Antibody, clone 9G7.1

  • 产品介绍
  • merck millipore,默克密理博,MABC111,Anti-STK3/MST2 Antibody, clone 9G7.1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, HIHC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABC111
    描述 Anti-STK3/MST2 Antibody, clone 9G7.1
    Alternate Names
    • Serine/threonine-protein kinase Krs-1
    • Serine/threonine-protein kinase 3
    • Mammalian STE20-like protein kinase 2
    • MST-2
    • STE20-like kinase MST2
    背景信息 Mammalian Ste20-like kinase 2 (MST2) is a serine/threonine kinase found in the kidney, placenta, heart, lung, and brain. It regulates organ size, cell proliferation, tumorigenesis, and apoptosis. Under conditions of cell stress, such as oxidative damage, MST2 is cleaved by caspase-3, and is irreversibly autophosphorylated at Thr180. Activated MST2 forms a stable complex with STK3 and triggers a signaling cascade which inhibits the translocation of YAP1 to the nucleus and consequent suppression of YAP1-mediated apoptosis.
    产品信息
    格式 Purified
    控制
    • Rat kidney tissue lysate
    演示 Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
    应用
    应用 Anti-STK3/MST2 Antibody, clone 9G7.1 detects level of STK3/MST2 & has been published & validated for use in Western Blotting & IHC.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected STK3/MST2 in human placenta tissues, normal human kidney tissue and human kidney cancer tissue.
    生物信息
    免疫原品种 GST-tagged recombinant protein corresponding to human STK3/MST2.
    克隆 9G7.1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgMκ
    品种反应性 RatHuman
    Species Reactivity Note Demonstrated to react with Rat and Human.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_006272
    基因符号
    • MST2
    • STK3
    • KRS1
    纯化方法 Purified by ion-exchange chromatography
    UniProt编号
    • Q13188
    产品使用声明
    质量保证 Evaluated by Western Blot in rat kidney tissue lysate.

    Western Blot Analysis: 0.25 µg/mL of this antibody detected STK3/MST2 in 10 µg of rat kidney tissue lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABC111,Anti-STK3/MST2 Antibody, clone 9G7.1

上一件merck millipore产品:merck millipore,默克密理博,6410-OP,OmniPur Neutralization Solution - Calbiochem
下一件merck millipore产品:merck millipore,默克密理博,PC474,Anti-PCNA (247-261) (Ab-5) Rabbit pAb



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