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品种反应性 主要应用 宿主 格式 抗体类型 Rb, H, M, R WB M Ascites Monoclonal Antibody 描述 产品目录编号 MAB5578 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-NMDAR2D Antibody 产品信息 格式 Ascites 控制 - Rat forebrain or cerebellum.
演示 Liquid. 应用 应用 Anti-NMDAR2D Antibody detects level of NMDAR2D & has been published & validated for use in WB. 主要应用 - Western Blotting
应用说明 Western blot: 1:500-1:1,000 on rat brain lysate.
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Recombinant protein from rat NMDAR2D. 克隆 1G9.39A5 宿主 Mouse 特异性 NMDAR2D, C-terminal. By Western blot the antibody reacts with a weak band at ~145. An additional band at ~75 kDa may be seen depending on sample and antibody concentration used. 同种型 IgG2b 品种反应性 RabbitHumanMouseRat 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_000836.2
Entrez基因汇总 N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). 基因符号 - NMDAR2D
- GRIN2D
- EB11
- Glutamate
- NR2D
UniProt编号 - O15399
UniProt汇总 FUNCTION: SwissProt: O15399 # NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
SIZE: 1336 amino acids; 143560 Da
SUBUNIT: Interacts with PDZ domains of INADL and DLG4 (By similarity). Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B).
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
SIMILARITY: SwissProt: O15399 ## Belongs to the glutamate-gated ion channel (TC 1.A.10) family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
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下一件merck millipore产品：merck millipore,默克密理博,234400,Complement, Rabbit Serum
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