merck millipore,默克密理博,492035,NSC 721648 - CAS 872726-44-8

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Merck Millipore 默克密理愽

merck millipore,默克密理博,492035,NSC 721648 - CAS 872726-44-8 - Calbiochem

经验配方	CAS号
C₁₅H₁₂FNO₂S	872726-44-8

描述
概述	A cell-permeable benzothiazole compound that exhibits potent in vitro antiproliferative activity against HCC 2998, IGROV1, MCF-7, MDA 468, SR, and T-47D (GI₅₀ <1 nM), while showing much reduced effect against 50 other human tumor cells in a panel screening. Although it is a high affinity AhR ligand (IC₅₀ = 25 nM; K_i = 6.8 nM in a TCDD competitive binding study) and a known CYP1A1 inducer, neither property can fully account for its antitumor activity.
产品目录编号	492035
品牌系列	Calbiochem®
同义词	5-Fluoro-2-(3,4-dimethoxyphenyl)benzothiazole, GW 610; PMX 610

参考
参考	Aiello, S., et al. 2008. J. Med. Chem. 51, 5135. Mortimer, C.G., et al. 2006. J. Med. Chem. 49, 179.

生物信息
纯度	≥97% by HPLC

理化信息
溶解度	DMF or DMSO

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Standard Handling
储存	+2°C to +8°C
避光	Protect from light
无需冷冻	No
特殊指南	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

包装信息
惰性气体下包装	Packaged under inert gas

merck millipore,默克密理博,492035,NSC 721648 - CAS 872726-44-8 - Calbiochem

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