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merck millipore,默克密理博,MAB5372,Anti-Astrocytomas Antibody, a marker for Low Grade Astrocytoma, clone J1-31
产品名称:Anti-Astrocytomas Antibody, a marker for Low Grade Astrocytoma, clone J1-31
产品型号:MAB5372
Detect Astrocytomas using this Anti-Astrocytomas Antibody, a marker for Low Grade Astrocytoma, clone J1-31 validated for use in WB, IC, IH(P).
merck millipore,默克密理博,MAB5372,Anti-Astrocytomas Antibody, a marker for Low Grade Astrocytoma, clone J1-31
- 产品介绍
- merck millipore,默克密理博,MAB5372,Anti-Astrocytomas Antibody, a marker for Low Grade Astrocytoma, clone J1-31
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, Gp, H, M ICC, WB M Ascites Monoclonal Antibody 描述 产品目录编号 MAB5372 Replaces MAB5314 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Astrocytomas Antibody, a marker for Low Grade Astrocytoma, clone J1-31 产品信息 格式 Ascites 演示 Ascites fluid. Liquid. 应用 应用 Detect Astrocytomas using this Anti-Astrocytomas Antibody, a marker for Low Grade Astrocytoma, clone J1-31 validated for use in WB, IC, IH(P). 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Western blot: reducing conditions, recognizes a 30kDa protein {Singh, R et al (1986) Biosci Rep 6(1):73-80.
Immunohistochemistry The antibody works on paraffin embedded tissue sections.
Immunocytochemistry
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Human cerebral white matter plaque materials from a multiple sclerosis patient. 表位 a marker for Low Grade Astrocytoma 克隆 J1-31 宿主 Mouse 特异性 The antibody recognizes an intracellular protein antigen (MW 30 kDa) expressed by human and rat astrocytes and other specialized glia (Muller cells of the retina, Bergmann fibers of the cerebellar cortex, tanycytes of the hypothalamus and ciliated ependymal cells) in the central nervous system (CNS).The antibody has recently been found to be a specific marker for low grade astrocytoma in human brain tissue. The antibody is able to distinguish between low grade astrocytoma and normal reactive gliosis (patent application filed).
Monoclonal antibody J1-31 was raised against crude homogenate of brain tissue from a multiple sclerosis (MS) patient (autopsy sample; Malhotra et al.: Microbios Letters 26:151-157, 1984). In human brain, MAb J1-31 recognizes an intracellular protein antigen (J1-31 antigen), which bands at approximately 30,000 daltons under reducing conditions for sodium dodecyl sulfate gel electrophoresis (Singh et al.: Bioscience Reports 6:73-79, 1986). By immunofluorescence microscopy, MAb J1-31 stains those cells that are also stained by antiserum to glial fibrillary acidic protein (GFAP), namely astrocytes, retinal Muller cells, and tanycytes in the ependyma (Predy et al.: Bioscience Reports 7:491-502, 1987). In addition, MAb J1-31 stains ciliated ependymal cells that do not express GFAP {Malhotra, SK (1989) J Neurosci Res. 22(1):36-49}.同种型 IgM 品种反应性 RatGuinea PigHumanMouse 抗体类型 Monoclonal Antibody 产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
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