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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M ChIP, WB, IHC Rb Serum Polyclonal Antibody 描述 产品目录编号 ABE567 描述 Anti-THAP11 Antibody Alternate Names - THAP11
- THAP domain-containing protein 11
背景信息 THAP11 (Ronin) is a transcriptional repressor which is predominantly expressed in embryonic stem (ES) cells. It contains a THAP-type zinc finger domain which is characteristic of the THAP 11 family members. In ES cells, THAP11 interacts with the transcriptional co-regulator HCF-1, to recruit chromatin-modifying proteins such as members of the polycomb family of proteins, to induce gene repression. THAP11 targets genes involved in metabolism, transcriptional initiation, and messenger RNA splicing. It plays an important role in maintaining the pluripotent state of ES cells. 产品信息 格式 Serum 演示 Flow through from affinity depleted rabbit polyclonal serum containing 0.05% sodium azide. 应用 应用 Anti-THAP11 Antibody is a highly specific rabbit polyclonal antibody, that targets Ronin & has been tested in western blotting, IP & IHC. 主要应用 - Chromatin Immunoprecipitation (ChIP)
- Western Blotting
- Immunohistochemistry
应用说明 Western Blotting Analysis: A representative lot of an affinity purfied version of this antibody detected THAP11 in tested cell lysates (Parker, J. B., et al. (2012). Mol Cell Biol. 32(9):1654-1670.).
Immunoprecipitation Analysis: A representative lot of an an affinity purfied version of this antibody immunoprecipitated THAP11 in tested cell lysates (Parker, J. B., et al. (2012). Mol Cell Biol. 32(9):1654-1670.).
Chromatin Immunoprecipitation Analysis: A representative lot of an an affinity purfied version of this antibody immunoprecipitated THAP11 in SW620 cell lysates (Parker, J. B., et al. (2012). Mol Cell Biol. 32(9):1654-1670.).
Immunohistochemistry Analysis: A representative lot of an an affinity purfied version of this antibody detected THAP11 in normal colon epithelium and colon adenocarcinoma tissues, and in lymph node metastasis tissues (Parker, J. B., et al. (2012). Mol Cell Biol. 32(9):1654-1670.).生物信息 免疫原品种 Recombinant protein corresponding to human THAP11. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_065190
基因符号 - THAP11
纯化方法 Unpurified UniProt编号 - Q96EK4
产品使用声明 质量保证 Evaluated by Western Blotting in HUVEC cell lysate.
Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected THAP11 in 10 µg of HUVEC cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µL
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