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merck millipore,默克密理博,AB1258,Anti-Cytochrome P450 Enzyme CYP1A1 Antibody
产品名称：Anti-Cytochrome P450 Enzyme CYP1A1 Antibody
产品型号：AB1258
Anti-Cytochrome P450 Enzyme CYP1A1 Antibody detects level of Cytochrome P450 Enzyme CYP1A1 & has been published & validated for use in IH & WB.
merck millipore,默克密理博,AB1258,Anti-Cytochrome P450 Enzyme CYP1A1 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB, IHC Rb Serum Polyclonal Antibody 描述 产品目录编号 AB1258 Replaces MAB3522 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Cytochrome P450 Enzyme CYP1A1 Antibody 产品信息 格式 Serum 演示 Rabbit antiserum. Liquid, no preservatives. 应用 应用 Anti-Cytochrome P450 Enzyme CYP1A1 Antibody detects level of Cytochrome P450 Enzyme CYP1A1 & has been published & validated for use in IH & WB. 主要应用 - Western Blotting
- Immunohistochemistry
应用说明 Western blot
Immunohistochemistry
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Synthetic peptide 宿主 Rabbit 特异性 Reacts with human cytochrome P450 CYP1A1 in human placental microsomal fraction and to recombinant human CYP1A1. 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_000499.2
Entrez基因汇总 This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. 基因符号 - AHH
- CYP1A1
- CP11
- P1-450
- CYPIA1
- P450-C
- CYP1
- P450DX
- P450-P1
- AHRR
UniProt编号 - P04798
UniProt汇总 FUNCTION: SwissProt: P04798 # Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
SIZE: 512 amino acids; 58165 Da
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
TISSUE SPECIFICITY: Lung, lymphocytes and placenta.
SIMILARITY: SwissProt: P04798 ## Belongs to the cytochrome P450 family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
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