merck millipore,默克密理博,MAB4314X,Anti-CD93 Antibody, clone R139, Alexa Fluor 488 conjugated

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merck millipore,默克密理博,MAB4314X,Anti-CD93 Antibody, clone R139, Alexa Fluor 488 conjugated
产品名称：Anti-CD93 Antibody, clone R139, Alexa Fluor 488 conjugated
产品型号：MAB4314X
Detect CD93 using this Anti-CD93 Antibody, clone R139, Alexa Fluor 488 conjugated validated for use in FC.

merck millipore,默克密理博,MAB4314X,Anti-CD93 Antibody, clone R139, Alexa Fluor 488 conjugated

产品介绍

merck millipore,默克密理博,MAB4314X,Anti-CD93 Antibody, clone R139, Alexa Fluor 488 conjugated

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	FC	M	AlexaFluor®488	Monoclonal Antibody

描述
产品目录编号	MAB4314X
品牌系列	Chemicon®
商名	Chemicon
描述	Anti-CD93 Antibody, clone R139, Alexa Fluor® 488 conjugated
Alternate Names	Complement C1q Receptor

产品信息
格式	AlexaFluor®488
演示	Purified immunoglobulin conjugated to Alexa Fluor® 488. Liquid in Phosphate buffer with 15 mg/mL BSA as a stabilizer and 0.1% sodium azide

应用
应用	Detect CD93 using this Anti-CD93 Antibody, clone R139, Alexa Fluor 488 conjugated validated for use in FC.
主要应用	Flow Cytometry
应用说明	Immunocytochemistry: Recommended antibody dilution: 5-10 μg/ml Fixative: 4% Paraformaldehyde / PBS Blocking buffer: 2% BSA / 2% Normal serum / PBS Dilution Buffer: 2% BSA / 2% Normal serum / PBS Incubation Times/Temperature: 1 hour at room temperature Recommended control tissue: Positive: U937 monocytes; Negative: T cells FACS Analysis: Suggested dilution/number of cells: 2 μg/million cells Fixation/Permeabilization used: 1% Paraformaldehyde / PBS Recommended controls: U937 Monocytes Optimal working dilutions must be determined by end user.

生物信息
免疫原品种	C1q collagen like domain binding proteins
克隆	R139
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
特异性	This antibody recognizes human CD93 (C1qRp), a 90-120kD protein that is highly expressed on monocytes/macrophages, neutrophils and granulocytes. CD93 is not expressed upon T and B lymphocytes. C1qRp binds C1q, the recognition subunit of the first component (C1) of the complement pathway, as well as MBL (Mannose-binding-lectin) and SPA (Pulmonary Surfactant Protein A). However, CD93 is not necessary for the binding of C1q or for inducing C1q-mediated enhancement of phagocytic activity.Recent evidence suggests that CD93 may define a new human stem cell population with hematopoietic and hepatic potential3.
同种型	IgG2b
品种反应性	Human
抗体类型	Monoclonal Antibody
Entrez基因编号	NM_012072.3
Entrez基因汇总	The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton.
基因符号	C1qRP CD93 MXRA4 C1qRp C1qR(P) C1qR dJ737E23.1 C1QR1 CDw93 p
UniProt编号	Q9NPY3
UniProt汇总	FUNCTION: SwissProt: Q9NPY3 # Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion. SIZE: 652 amino acids; 68560 Da SUBUNIT: Interacts with HCV core protein. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: Highly expressed in endothelial cells, platelets, cells of myeloid origin, such as monocytes and neutrophils. Not expressed in cells of lymphoid origin. PTM: N- and O-glycosylated. SIMILARITY: SwissProt: Q9NPY3 ## Contains 1 C-type lectin domain. & Contains 5 EGF-like domains.

产品使用声明
使用声明	Alexa Fluor® is a registered trademark of Molecular Probes, Inc. Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

产品使用声明

使用声明

Alexa Fluor® is a registered trademark of Molecular Probes, Inc.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 24 months.

包装信息
数量	100 µg

merck millipore,默克密理博,MAB4314X,Anti-CD93 Antibody, clone R139, Alexa Fluor 488 conjugated

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