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纯度 ≥97% by SDS-PAGE 描述 概述 Recombinant, human neuregulin 1-β1/heregulin 1-β1 epidermal growth factor-like domain (NRG1-β1/HRG1-β1 EGF Domain), consisting of amino acids 176-246 and expressed in E. coli. All NRG1 isoforms contain an EGF-like domain that is required for binding directly to the ErbB3 or ErbB4 receptor tyrosine kinases. 产品目录编号 492029 品牌系列 Calbiochem®
参考 参考 Buonanno, A., and Fischbach, G.D. 2001. Curr. Opin. Neurobiol. 11, 287.
Adlkofer, K. and Lai, C. 2000. Glia 29, 104.
Garratt, A.N. et al. 2000. BioEssays 22, 987.
Karey, K.P., et al. 1988. Cancer Res. 48, 4083.产品信息 形式 Lyophilized 配方 Lyophilized from 0.2 µm filtered acetonitrile, TFA, BSA. Molar Mass 8000 生物信息 生物活性 ED₅₀ = 0.06-0.3 ng/ml as measured in a serum-free proliferation assay using MCF-7 human breast adenocarcinoma cells. 纯度 ≥97% by SDS-PAGE 理化信息 污染物 Endotoxin: ≤1.0 EU/µg protein 溶解度 PBS 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
无需冷冻 No
特殊指南 Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
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