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merck millipore,默克密理博,MAB3740,Anti-Protein Tyrosine Phosphatase µ Antibody, clone BK2
产品名称：Anti-Protein Tyrosine Phosphatase µ Antibody, clone BK2
产品型号：MAB3740
Anti-Protein Tyrosine Phosphatase μ Antibody, clone BK2 is an antibody against Protein Tyrosine Phosphatase μ for use in IC, IP & WB.
merck millipore,默克密理博,MAB3740,Anti-Protein Tyrosine Phosphatase µ Antibody, clone BK2
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Xn, B, H, M, R WB, ICC M Ascites Monoclonal Antibody 描述 产品目录编号 MAB3740 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Protein Tyrosine Phosphatase µ Antibody, clone BK2 Alternate Names - R-PTP-MU
- Receptor-type Protein-tyrosine Phosphatase mu
产品信息 格式 Ascites 演示 Ascites fluid 应用 应用 Anti-Protein Tyrosine Phosphatase μ Antibody, clone BK2 is an antibody against Protein Tyrosine Phosphatase μ for use in IC, IP & WB. 主要应用 - Western Blotting
- Immunocytochemistry
应用说明 Western blot (1:8,000)
Immunoprecipitation
Immunofluorescence (1:200)
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Corresponds to amino acids 42-60 of human PTPμ 克隆 BK2 宿主 Mouse 特异性 Recognizes human PTPμ (Protein Tyrosine Phosphatase mu), a Receptor-type protein-tyrosine phosphatase. This antibody recognizes the extracellular domain of PTPμ. 同种型 IgG2a 品种反应性 XenopusBovineHumanMouseRat 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_002845.3
- NM_001105244.1
Entrez基因汇总 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. 基因符号 - EC 3.1.3.48
- PTPRM
- R-PTP-MU
- RPTPU
- RPTPM
- PTPRL1
- R-PTP-mu
- hR-PTPu
- MGC166994
UniProt编号 - P28827
UniProt汇总 FUNCTION: SwissProt: P28827 # Involved in cell-cell adhesion through homophilic interactions. May play a key role in signal transduction and growth control.
SIZE: 1452 amino acids; 163633 Da
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
SIMILARITY: SwissProt: P28827 ## Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily. & Contains 4 fibronectin type-III domains. & Contains 1 Ig-like C2-type (immunoglobulin-like) domain. & Contains 1 MAM domain. & Contains 2 tyrosine-protein phosphatase domains.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µL
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