merck millipore,默克密理博,MAB3562,Anti-Sodium/Iodine Symporter Antibody, clone 2-2

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	WB, IHC	M	Purified	Monoclonal Antibody

描述
产品目录编号	MAB3562
品牌系列	Chemicon®
商名	Chemicon
描述	Anti-Sodium/Iodine Symporter Antibody, clone 2-2
Alternate Names	NIS Na+/I- Symporter

产品信息
格式	Purified
演示	Liquid. Buffer = 0.02M Phosphate buffer, 0.25M NaCl with 0.1% sodium azide.

应用
应用	Anti-Sodium/Iodine Symporter Antibody, clone 2-2 detects level of Sodium/Iodine Symporter & has been published & validated for use in IH & WB.
主要应用	Western Blotting Immunohistochemistry
应用说明	Immunoblotting. The antibody recognizes a major band at ~97 kDa and minor bands at 15 kDa, 30 kDa, 68 kDa and 160 kDa. Immunohistochemistry on frozen tissues. Optimal working dilutions must be determined by end user.

生物信息
免疫原品种	Synthetic peptide corresponding to amino acids 37-54 of human NIS.
克隆	2-2
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
特异性	Sodium/Iodide Symporter (NIS)
同种型	IgG1
品种反应性	Human
抗体类型	Monoclonal Antibody
Entrez基因编号	NM_000453.1
Entrez基因汇总	The sodium-iodide symporter (NIS), a member of the sodium/solute symporter family, actively transports iodide across the basolateral plasma membrane of the thyroid follicular cells.[supplied by OMIM]
基因符号	-cotransporter) SLC5A5 +I NIS Na -symporter)
UniProt编号	Q92911
UniProt汇总	FUNCTION: SwissProt: Q92911 # Mediates iodide uptake in the thyroid gland. SIZE: 643 amino acids; 68666 Da SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors. DISEASE: SwissProt: Q92911 # Defects in SLC5A5 are the cause of iodide transport defect (ITD) [MIM:274400]. ITD is characterized by an inability of the thyroid to maintain a concentration difference of readily exchangeable iodine between the plasma and the thyroid gland. It is a cause of congenital hypothyroidism. SIMILARITY: SwissProt: Q92911 ## Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain at 2-8°C in undiluted aliquots for up to 6 months.

包装信息
数量	100 µg

merck millipore,默克密理博,MAB3562,Anti-Sodium/Iodine Symporter Antibody, clone 2-2

whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech