merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB3422,Anti-Histone Antibody, clone H11-4

  • merck millipore,默克密理博,MAB3422,Anti-Histone Antibody, clone H11-4

    产品名称：Anti-Histone Antibody, clone H11-4
    产品型号：MAB3422
    Detect Histone with Anti-Histone Antibody, clone H11-4 (Mouse Monoclonal Antibody), that has been shown to work in ICC, IHC & WB.

    merck millipore,默克密理博,MAB3422,Anti-Histone Antibody, clone H11-4

  • 产品介绍
  • merck millipore,默克密理博,MAB3422,Anti-Histone Antibody, clone H11-4

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Ht, Ma, H, B, R, Xn, OpWB, ICC, IHCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB3422
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Histone Antibody, clone H11-4
    背景信息 There are 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. The five major classes of histones are H1/H5, H2A, H2B, H3, and H4. Histones H2A, H2B, H3 and H4 are known as the core histones, while histones H1 and H5 are known as the linker histones. Histones feature a main globular domain and a long N terminal tail which are involved with the structure of the nucleosomes of the 'beads on a string' structure. They are the chief protein components of chromatin, acting as spools around which DNA winds, and play a role in gene regulation.
    产品信息
    格式 Purified
    控制
    • All tissue
    演示 Purified mouse monoclonal IgG1 in buffer containing 0.02M phosphate buffer, pH 7.6 with 0.25M NaCl and 0.1% sodium azide
    应用
    应用 Detect Histone with Anti-Histone Antibody, clone H11-4 (Mouse Monoclonal Antibody), that has been shown to work in ICC, IHC & WB.
    主要应用
    • Western Blotting
    • Immunocytochemistry
    • Immunohistochemistry
    应用说明 Western Blot Analysis:
    1:500 dilution of a previous lot was used.

    Immunocytochemistry:
    A 1-5 µg/mL concentration of a previous lot was used on Immunocytochemistry.

    Immunohistochemistry:
    A 1-5 μg/mL concentration of a previous lot was used on Immunohistochemistry.

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Purified nuclear fractions of HeLa cells
    克隆 H11-4
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 The antibody binds specifically to an antigen determinant, which is present on all five histone proteins. The antibody recognizes the histones H1, H2A, H2B, H3 and H4 with comparable sensitivity.
    同种型 IgG1
    品种反应性 HamsterMammalsHumanBovineRatXenopusOpossum
    Species Reactivity Note Due to the highly conserved nature of histones, this antibody is predicted to have wide species reactivity.
    抗体类型 Monoclonal Antibody
    Entrez基因汇总 Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.
    纯化方法 Protein A purfied
    产品使用声明
    质量保证 Routinely evaluated by Western Blot on Jurkat lysates.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 6 months at 2-8ºC in undiluted aliquots from date of receipt.
    The Iyophilized antibody is stable at 2–8°C. Store the reconstituted antibody in aliquots at -15 to -25°C for up to 12 months.Repeated freezing and thawing should be avoided.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB3422,Anti-Histone Antibody, clone H11-4

上一件merck millipore产品：merck millipore,默克密理博,MAB2254,Anti-Tropomyosin Antibody, clone 15D12.2
下一件merck millipore产品：merck millipore,默克密理博,HTS075M,ChemiScreen™ Membrane Preparation Recombinant Human M5 Muscarinic Acetylcholine Receptor


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