merck millipore,默克密理博,MAB3418B,Anti-MAP2 Antibody, clone AP20, Biotin Conjugated

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
Ch, H, M, R, B	ICC	M	Biotin	Monoclonal Antibody

描述
产品目录编号	MAB3418B
描述	Anti-MAP2 Antibody, clone AP20, Biotin Conjugated
Alternate Names	MAP2 Microtubule-associated protein 2 MAP-2
背景信息	The microtubule-associated protein 2 (MAP-2) is an abundant neuronal cytoskeletal protein that binds to tubulin, stabilizes microtubules (Herzog and Weber, 1978), and is an excellent marker for neurons. MAP-2 is essential for the development and maintenance of neuronal morphology (Matus, 1991). Three primary isoforms of MAP-2, the high molecular weight MAP2a and MAP2b, and the low molecular weight MAP2c (resulting from alternate splicing of the MAP2 gene), have been identified in neurours. (Chung et al., 1996). The low molecular weight isoform, MAP2c, is expressed in developing brain and is down-regulated during brain maturation, whereas the high molecular weight MAP2b is expressed in both developing and adult brain. The MAP2a appears only after brain maturation (Tucker, 1990). All these forms bind to microtubules through a domain near the carboxyl terminus that contains either three or four similar repeats of a 31-amino-acid motif (Lewis et al., 1988). MAP-2 together with MAP-4 and tau proteins belong to the family of thermostable proteins associated with microtubules.

产品信息
格式	Biotin
控制	Rat cortex tissue
演示	Purified mouse monoclonal IgG conjugated to Biotin in PBS with 0.1% sodium azide and 15 mg/mL BSA.

应用
应用	Anti-MAP2 Antibody, clone AP20, Biotin Conjugated is an antibody against MAP2 for use in ICC.
主要应用	Immunocytochemistry
应用说明	Immunocytochemistry Analysis: A 1:25 dilution from a representative lot detected MAP2 in rat E18 primary cortex cells.

生物信息
免疫原品种	Bovine brain microtubule protein
克隆	AP20
宿主	Mouse
同种型	IgG
品种反应性	ChickenHumanMouseRatBovine
Species Reactivity Note	Demonstrated to react with Rat. Predicted to react with Chicken, Human, and Mouse based on 100% sequence homology. Predicted to react with Bovine based on immunogen design.
抗体类型	Monoclonal Antibody
基因符号	Mtap2 Map2
纯化方法	Protein G purified
UniProt编号	Q0IIA8

产品使用声明
质量保证	Evaluated by Immunohistochemistry in rat cortex tissue. Immunohistochemistry Analysis: A 1:25 dilution of this antibody detected MAP2 in rat cortex tissue.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain refrigerated at 2-8 °C in undiluted aliquots for up to 6 months from date of receipt.

包装信息
数量	100 µL

merck millipore,默克密理博,MAB3418B,Anti-MAP2 Antibody, clone AP20, Biotin Conjugated

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