merck millipore,默克密理博,MABN613,Anti-Potassium channel Kv2.1 Antibody, clone L80/21

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
M, R	WB	M	Purified	Monoclonal Antibody

描述
产品目录编号	MABN613
描述	Anti-Potassium channel Kv2.1 Antibody, clone L80/21
Alternate Names	Voltage-gated potassium channel subunit Kv2.1 Potassium voltage-gated channel subfamily B member 1 Delayed rectifier potassium channel 1 DRK1
背景信息	Voltage-gated potassium channel subunit Kv2.1 (Kv2.1) is also called potassium voltage-gated channel subfamily B member 1 (KCNB1) or delayed rectifier potassium channel 1 (DRK1). Kv2.1 is a voltage-gated potassium ion channel that is expressed in the brain (cell bodies and dendrites of neurons but not axons, as well as Schwann cells), atria, ventricle, skeletal muscle, cochlea, retina, lung and pulmonary arteries. It is involved in maintaining membrane potential and modulating electrical excitability of both neurons and muscle cells. It is thought that Kv2.1 has a role in the muscle tone of the pulmonary system, as the expression Kv2.1 in pulmonary smooth muscle has been found to be reduced in chronic hypoxic pulmonary hypertension.

产品信息
格式	Purified
控制	Rat brain tissue lysate
演示	Purified mouse monoclonal IgG3κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	Detect Kv2.1 using this mouse monoclonal antibody, Anti-Potassium channel Kv2.1 Antibody, clone L80/21 validated for use in western blotting & IHC (Paraffin).
主要应用	Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Potassium channel Kv2.1 in rat frontal cortex tissue. Western Blotting Analysis: A representative lot detected Potassium channel Kv2.1 in wild type mouse brain membrane tissue lysate, and demonstrated a loss of signal in Potassium channel Kv2.1 knock out mouse brain membrante tissue lysate (Prof. J. Trimmer, University of California, Davis.).

生物信息
免疫原品种	Linear peptide corresponding to the C-terminus of rat Potassium channel Kv2.1.
表位	C-terminus
克隆	L80/21
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
特异性	This antibody recognizes the C-terminus of Potassium channel Kv2.1.
同种型	IgG3κ
品种反应性	MouseRat
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_037318
基因符号	Kcnb1
纯化方法	Protein G purified
UniProt编号	P15387

产品使用声明
质量保证	Evaluated by Western Blotting in rat brain tissue lysate. Western Blotting Analysis: 1 µg/mL of this antibody detected Potassium channel Kv2.1 in 10 µg of rat brain tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,MABN613,Anti-Potassium channel Kv2.1 Antibody, clone L80/21

whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech