merck millipore,默克密理博,MABN487,Anti-Cav3.2 Calcium Channel Subunit Antibody, clone N55/10

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
M	WB	M	Purified	Monoclonal Antibody

描述
产品目录编号	MABN487
描述	Anti-Cav3.2 Calcium Channel Subunit Antibody, clone N55/10
Alternate Names	Voltage-gated calcium channel subunit alpha Cav3.2 Cav3.2 Calcium Channel Subunit Voltage-dependent T-type calcium channel subunit alpha-1H Low-voltage-activated calcium channel alpha1 3.2 subunit
背景信息	Voltage-gated calcium channel subunit alpha Cav3.2 is also called Voltage-dependent T-type calcium channel subunit alpha-1H and Low-voltage-activated calcium channel alpha 1 3.2 subunit. Voltage-gated calcium channel subunit alpha Cav3.2 and other voltage-sensitive calcium channels (VSCC) are involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Voltage-gated calcium channel subunit alpha Cav3.2 is expressed in kidney, liver, heart, brain, and isoform 2 appears to be testis specific. Voltage-gated calcium channel subunit alpha Cav3.2 defects can increase susceptibility to epilepsy, idiopathic generalized type 6 (EIG6) and epilepsy, childhood absence type 6 (ECA6).

产品信息
格式	Purified
控制	NIH/3T3 cell lysate
演示	Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	Detect Cav3.2 using this mouse monoclonal antibody, Anti-Cav3.2 Calcium Channel Subunit Antibody & clone N55/10 validated for use in western blotting.
主要应用	Western Blotting
应用说明	Immunohistochemistry Analysis: A representative lot detected Cav3.2 Calcium Channel Subunit in wild type mice and demonstrated a loss of signal in Cav3.2 knock out mice (Prof. J. Trimmer, University of California, Davis.). Western Blotting Analysis: A representative lot detected Cav3.2 Calcium Channel Subunit in HEK293 cell lysates expressing Flag-tagged Cav3.2 and demonstrated a loss of signal in HEK293 cell lysates expressing Flag-tagged Kv2.1 and Flag-tagged Cav3.1 (Prof. J. Trimmer, University of California, Davis.).

生物信息
免疫原品种	Recombinant protein corresponding to human Cav3.2 Calcium Channel Subunit.
克隆	N55/10
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
特异性	This antibody does not cross react with human Cav3.1 Calcium Channel Subunit (Prof. J. Trimmer, University of California, Davis.).
同种型	IgG1κ
品种反应性	Mouse
Species Reactivity Note	Demonstrated to react with Mouse. Predicted to react with human based upon immunogen design.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_001005407
基因符号	CACNA1H
纯化方法	Protein G purified
UniProt编号	O95180

产品使用声明
质量保证	Evaluated by Western Blotting in NIH/3T3 cell lysate. Western Blotting Analysis: 1 µg/mL of this antibody detected Cav3.2 Calcium Channel Subunit in 10 µg of NIH/3T3 cell lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,MABN487,Anti-Cav3.2 Calcium Channel Subunit Antibody, clone N55/10

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