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merck millipore,默克密理博,MAB3126,Anti-Calnexin Antibody, ER marker, clone C8.B6
产品名称:Anti-Calnexin Antibody, ER marker, clone C8.B6
产品型号:MAB3126
Detect Calnexin using this Anti-Calnexin Antibody, ER marker, clone C8.B6 validated for use in IC, IH, IP & WB.
merck millipore,默克密理博,MAB3126,Anti-Calnexin Antibody, ER marker, clone C8.B6
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H WB, ICC, IHC M Ascites Monoclonal Antibody 描述 产品目录编号 MAB3126 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Calnexin Antibody, ER marker, clone C8.B6 Alternate Names - Phosphoprotein pp90
- IP90 Protein
- Integral Membrane Protein IP90
背景信息 Calnexin is a Ca++ binding protein found in endoplasmic reticulum membranes that binds to specific n-linked oligosaccharides found on newly synthesized proteins. It may play role in protein folding or retention and degradation of misfolded proteins in the endoplasmic reticulum. 产品信息 格式 Ascites 控制 - Widely expressed
演示 Ascites fluid containing no preservatives. 应用 应用 Detect Calnexin using this Anti-Calnexin Antibody, ER marker, clone C8.B6 validated for use in IC, IH, IP & WB. 主要应用 - Western Blotting
- Immunocytochemistry
- Immunohistochemistry
应用说明 Immunohistochemistry on frozen tissue sections: 1:500-1:2,000
Immunocytochemistry: 1:100--1:250
Immunoblotting: 1:200-1:2,000
Immunoprecipitation: 1:200-1:1,000
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Recombinant human calnexin 表位 ER marker 克隆 C8.B6 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 Recognizes Calnexin. 同种型 IgG1 品种反应性 MouseHuman 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_001746.3
- NM_001024649.1
Entrez基因汇总 This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. 基因符号 - calnexin
- CANX
- P90
- FLJ26570
- CNX
- IP90
- p90
纯化方法 Unpurified UniProt编号 - P27824
UniProt汇总 FUNCTION: SwissProt: P27824 # Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.
SIZE: 592 amino acids; 67568 Da
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
SIMILARITY: SwissProt: P27824 ## Belongs to the calreticulin family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 100 µg
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