merck millipore,默克密理愽
  • merck millipore,默克密理博,342500,FK-506, Streptomyces sp. - CAS 104987-11-3 - Calbiochem

  • merck millipore,默克密理博,342500,FK-506, Streptomyces sp. - CAS 104987-11-3 - Calbiochem

    产品名称：FK-506, Streptomyces sp. - CAS 104987-11-3 - Calbiochem
    产品型号：342500
    Immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2.

    merck millipore,默克密理博,342500,FK-506, Streptomyces sp. - CAS 104987-11-3 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,342500,FK-506, Streptomyces sp. - CAS 104987-11-3 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₄₄H₆₉NO₁₂104987-11-3
    描述
    概述 Immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca2+ release. Inhibits the Ca2+-dependent phosphatase, Protein Phosphatase 2B (Calcineurin; Cat. No. 539568), as well as Na+,K+-ATPase in nephron segments. Also shown to inhibit aldosterone-induced synthesis of Giα-3 protein.
    产品目录编号 342500
    品牌系列 Calbiochem®
    同义词 Tacrolimus
    参考
    参考 Asano, K., et al. 1996. In Vivo 10, 537.
    McCall, E., et al. 1996. Circ. Res. 79, 1110.
    Raufman, J.P., et al. 1996. J. Biol. Chem. 271, 19877.
    Rokaw, M.D., et al. 1996. Am. J. Physiol. 271, C194.
    产品信息
    CAS号 104987-11-3
    具有ATP竞争性 N
    形式 Off-white solid
    Hill配方 C₄₄H₆₉NO₁₂
    Molar Mass 804.1
    可逆 N
    结构配方图像
    生物信息
    主靶 Immunosuppressant that blocks T cell proliferation
    纯度 ≥98% by TLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO or MeOH
    GHS安全信息
    RTECS KD4200000
    安全信息
    R相 R: 25

    Toxic if swallowed.
    S相 S: 36/37/39-45

    Wear suitable protective clothing, gloves and eye/face protection.
    In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Toxic
    有害材料注意事项： Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
    储存 +2°C to +8°C
    防潮 Protect from moisture
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

    merck millipore,默克密理博,342500,FK-506, Streptomyces sp. - CAS 104987-11-3 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,MAB3126,Anti-Calnexin Antibody, ER marker, clone C8.B6
下一件merck millipore产品：merck millipore,默克密理博,616382,Nα-Tosyl-Lys Chloromethyl Ketone, Hydrochloride - CAS 4238-41-9 - Calbiochem


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