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merck millipore,默克密理博,MAB2624,Anti-Endomucin Antibody, clone V.5C7
产品名称:Anti-Endomucin Antibody, clone V.5C7
产品型号:MAB2624
Anti-Endomucin Antibody, clone V.5C7 detects level of Endomucin & has been published & validated for use in WB, IP, IH, FC.
merck millipore,默克密理博,MAB2624,Anti-Endomucin Antibody, clone V.5C7
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M FC, WB, IHC R Purified Monoclonal Antibody 描述 产品目录编号 MAB2624 描述 Anti-Endomucin Antibody, clone V.5C7 Alternate Names - Endomucin-1/2
- Endomucin-2
- Gastric cancer antigen Ga34
- Mucin-14
- MUC-14
背景信息 Endomucin is an endothelial sialomucin belonging to a class of glycoproteins characterized by their high levels of O-glycosolation and rich quantities of sialic acid. It inhibits focal adhesion assembly and hinders extracellular matrix and cell interaction. Observed expression is highest in kidney heart, brain, liver, lung, spleen, and thymus. Endomucin is only found in endothelial cells. 产品信息 格式 Purified 控制 - bEND3 cell lysate
演示 Purified rat monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-Endomucin Antibody, clone V.5C7 detects level of Endomucin & has been published & validated for use in WB, IP, IH, FC. 主要应用 - Flow Cytometry
- Western Blotting
- Immunohistochemistry
应用说明 Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP of bEND cell lysate (Morgan, 1999).
Immunohistochemistry Analysis: A previous lot was used by an independent laboratory in immunhistochemical staining of frozen and paraffin-embedded tissue sections of mouse tongue, heart, uterus, brain, and small intestine (Morgan, 1999).
Flow Cytometry Analysis: A previous lot was used by an independent laboratory in FC of transfected COS-7 cells (Morgan, 1999).生物信息 免疫原品种 Mouse endothelial cells 克隆 V.5C7 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rat 同种型 IgG1κ 品种反应性 Mouse Species Reactivity Note Demonstrated to react with mouse. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_001156994
基因符号 - MUC-14
- MUC14
- EMCN2
纯化方法 Protein G UniProt编号 - Q9R0H2
UniProt汇总 FUNCTION: Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix (by similarity).
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein Potential.
TISSUE SPECIFICTY: Highly expressed in heart and kidney, followed by brain, spleen, thymus, liver and lung. Exclusively expressed in endothelial cells.
PTM: Highly O-glycosylated. Sialic acid-rich glycoprotein.产品使用声明 质量保证 Evaluated by Western Blot on mouse endothelioma cell line, bEND3, cell lysate.
Western Blot Analysis: 0.0025 µg/mL of this antibody detected Endomucin in 10 µg of bEND3 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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