merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB2022,Anti-Keratan Sulfate Antibody, clone EFG-11

  • merck millipore,默克密理博,MAB2022,Anti-Keratan Sulfate Antibody, clone EFG-11

    产品名称：Anti-Keratan Sulfate Antibody, clone EFG-11
    产品型号：MAB2022
    Anti-Keratan Sulfate Antibody, clone EFG-11 is an antibody against Keratan Sulfate for use in ELISA, RIA & WB.

    merck millipore,默克密理博,MAB2022,Anti-Keratan Sulfate Antibody, clone EFG-11

  • 产品介绍
  • merck millipore,默克密理博,MAB2022,Anti-Keratan Sulfate Antibody, clone EFG-11

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Sh, B, Ca, H, M, PoWB, ELISAMAscitesMonoclonal Antibody
    描述
    产品目录编号 MAB2022
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Keratan Sulfate Antibody, clone EFG-11
    产品信息
    格式 Ascites
    演示 Ascites liquid, no preservative.
    应用
    应用 Anti-Keratan Sulfate Antibody, clone EFG-11 is an antibody against Keratan Sulfate for use in ELISA, RIA & WB.
    主要应用
    • Western Blotting
    • ELISA
    应用说明 Western blot at 1:1000 - 1:4000

    ELISA at 1:5,000-1:20,000

    RIA at 1:30,000-1:500,000

    May be used in a competitive inhibition assay to measure keratan sulfate levels.
    生物信息
    免疫原品种 Human articular cartilage proteoglycan digested with chondroitinase ABC.
    克隆 EFG-11
    宿主 Mouse
    特异性 Recognizes 2-3 disaccharide units on both skeletal (type II) and corneal (type I) keratan sulfate chains either in isolated or proteoglycan-bound form. The epitope is resistant to proteolytic or alkaline cleavages and partially sensitive to keratanase or other endo-B-galactosidase treatment.
    同种型 IgG2b
    品种反应性 SheepBovineCanineHumanMousePig
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_002345.3
    Entrez基因汇总 This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.
    基因符号
    • lumican
    • LUM
    • SLRR2D
    • LDC
    UniProt编号
    • P51884
    UniProt汇总 SIZE: 338 amino acids; 38429 Da
    SUBUNIT: Binds to laminin (By similarity).
    SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix (By similarity).
    TISSUE SPECIFICITY: Cornea and other tissues.
    DEVELOPMENTAL STAGE: Present in the extracellular matrix of human articular cartilage at all ages, although its abundance is far greater in the adult. In the adult cartilage lumican exists predominantly in a glycoprotein form lacking keratan sulfate, whereas the juvenile form of the molecule is a proteoglycan.
    SIMILARITY: SwissProt: P51884 ## Belongs to the small leucine-rich proteoglycan (SLRP) family. Class II subfamily. & Contains 12 LRR (leucine-rich) repeats.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in convenient aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MAB2022,Anti-Keratan Sulfate Antibody, clone EFG-11

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下一件merck millipore产品：merck millipore,默克密理博,AB2290C3,Anti-MAP2, Cy3 Conjugate Antibody


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