merck millipore,默克密理愽
  • merck millipore,默克密理博,14-930M,IRE1, active

  • merck millipore,默克密理博,14-930M,IRE1, active

    产品名称：IRE1, active
    产品型号：14-930M


    merck millipore,默克密理博,14-930M,IRE1, active

  • 产品介绍
  • merck millipore,默克密理博,14-930M,IRE1, active

    描述
    产品目录编号 14-930M
    商名
    • Upstate
    描述 IRE1, active
    概述 Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
    产品信息
    演示 Protein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
    应用
    主要应用
    • Kinase Assay
    生物信息
    来源 N-terminal 6His-tagged, recombinant, human IRE1 amino acids 465-end expressed by baculovirus in Sf21 insect cells.
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_001433
    基因符号
    • IRE1
    • ERN1
    UniProt编号
    • O75460
    产品使用声明
    质量保证 Routinely evaluated by phosphorylation of MBP.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C
    包装信息
    数量 250 µg
    包装 Also available in 10μg size as catalog # 14-930 and in bulk as catalog # 14-930-K.

    merck millipore,默克密理博,14-930M,IRE1, active

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