merck millipore,默克密理博,IF006,Interferon-γ Protein, Recombinant rat

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merck millipore,默克密理博,IF006,Interferon-γ Protein, Recombinant rat
产品名称：Interferon-γ Protein, Recombinant rat
产品型号：IF006
The Interferon-gamma protein (or IFN-gamma protein) is a lymphoid factor that possesses potent anti-viral activity.

merck millipore,默克密理博,IF006,Interferon-γ Protein, Recombinant rat

产品介绍

merck millipore,默克密理博,IF006,Interferon-γ Protein, Recombinant rat

重要规格表

主要应用	品种	来源	纯度
CULT	Rat	E.coli	Greater than 97% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/ug) of IFN gamma.

描述
产品目录编号	IF006
品牌系列	Chemicon®
商名	Chemicon
描述	Interferon-γ Protein, Recombinant rat
概述	Interferon gamma is a lymphoid factor that possesses potent anti-viral activity. It has been shown to stimulate macrophages and NK cells. Recombinant Rat IFN gamma is a 15.6 kDa protein containing 135 amino acid residues.

产品信息
演示	The sterile filtered solution was lyophilized from PBS.

应用
应用	The Interferon-gamma protein (or IFN-gamma protein) is a lymphoid factor that possesses potent anti-viral activity.
主要应用	Cell Culture

生物信息
纯度	Greater than 97% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/ug) of IFN gamma.
来源	E.coli
品种	Rat
特异活性	The ED(50) as determined by a cytopathic affect inhibition assay with murine L929 cells challenged with EMC virus was <= 0.1 ng/ml, corresponding to a specific activity of >= 1 x 10(E7) units/mg.
UniProt编号	P01581 P01579
UniProt汇总	FUNCTION: SwissProt: P01579 # Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. SIZE: 166 amino acids; 19348 Da SUBUNIT: Homodimer. SUBCELLULAR LOCATION: Secreted. TISSUE SPECIFICITY: Released primarily from activated T lymphocytes. PTM: Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161. DISEASE: SwissProt: P01579 # In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis. SIMILARITY: SwissProt: P01579 ## Belongs to the type II (or gamma) interferon family.
细胞系类型	Epithelial Cells

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstitute in 5 mM Tris, pH 8.0 + 100 mM NaCl to a concentration of 1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4ºC for 1 week or -20ºC for future use. Reconstituted rat IFN gamma should be stored in undiluted aliquots at -20ºC. Avoid repeated freeze/thaw cycles.

储存和货运信息

存储条件

The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstitute in 5 mM Tris, pH 8.0 + 100 mM NaCl to a concentration of 1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4ºC for 1 week or -20ºC for future use. Reconstituted rat IFN gamma should be stored in undiluted aliquots at -20ºC. Avoid repeated freeze/thaw cycles.