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来源 纯度 HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free. Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE. 描述 产品目录编号 GF436 商名 - HumanKine®
描述 HumanKine® PDGFaa, Human Recombinant Xeno-Free Alternate Names - PDGFA,PDGF1
- Platelet Derived Growth Factor-AA
背景信息 Platelet-Derived Growth Factor (PDGF) is a dimer of A (17 kDa) and B (14 kDa) chains (AA, AB, or BB). Its receptors are transmembrane receptor tyrosine kinases, PDGF Receptors type A and B. The type A PDGF receptor binds all three PDGFs with high affinity, whereas the type B PDGF receptor is selective for PDGF-BB. PDGF signals as a growth and survival factor, as it is a potent activator of the PI3 Kinase pathway. PDGF signaling appears to play an essential role in the development of tumors of glial origin. 产品信息 配方 演示 Product is presented in 10mM HOAc and filtered through a 0.2 micron filter before lyophilization. 生物信息 纯度 Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE. 来源 HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free. UniProt编号 - P04085
产品使用声明 质量保证 Bioactivity assay: Determined bythe dose-dependent stimulation of the proliferation of 3T3 cells. ED50 is typically 200-1000 ng/ml. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added. 包装信息 数量 10 µg
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