merck millipore,默克密理愽
  • merck millipore,默克密理博,GF035,Ciliary Neurotrophic Factor Protein, Recombinant rat

  • merck millipore,默克密理博,GF035,Ciliary Neurotrophic Factor Protein, Recombinant rat

    产品名称：Ciliary Neurotrophic Factor Protein, Recombinant rat
    产品型号：GF035
    The Rat Ciliary Neurotrophic Factor (or CNTF protein) is a potent neural factor that was originally characterized as a survivability factor for chick ciliary neurons in vitro.

    merck millipore,默克密理博,GF035,Ciliary Neurotrophic Factor Protein, Recombinant rat

  • 产品介绍
  • merck millipore,默克密理博,GF035,Ciliary Neurotrophic Factor Protein, Recombinant rat

    重要规格表

    品种 来源 纯度
    RatE.coliGreater than 98% by SDS-PAGE and HPLC analysis
    描述
    产品目录编号 GF035
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Ciliary Neurotrophic Factor Protein, Recombinant rat
    概述 Ciliary Neurotrophic Factor (CNTF) is a potent neural factor that was originally characterized as a survivability factor for chick ciliary neurons in vitro. More recently, CNTF has been shown to promote survivability and differentiation of other neuronal cell types. Rat CNTF is a 22.7 kDa protein containing 199 amino acid residues.
    Alternate Names
    • CNTF
    产品信息
    演示 Sterile filtered, lyophilized from 5 mM Na Acetate, pH 6.5. Contains no preservative.
    应用
    应用 The Rat Ciliary Neurotrophic Factor (or CNTF protein) is a potent neural factor that was originally characterized as a survivability factor for chick ciliary neurons in vitro.
    应用说明 Concentration range for most in vitro applications is 0.01-10 ng/mL. Responding cells are (partial list): Ciliary and sympathetic neurons.
    生物信息
    纯度 Greater than 98% by SDS-PAGE and HPLC analysis
    来源 E.coli
    品种 Rat
    特异活性 The rat CNTF is fully biologically active when compared to standards. The ED(50) as determined by the dose-dependent proliferation of human TF-1 cells is <= 15-30 ng/mL.
    Entrez基因汇总 The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. In addition to the predominant monocistronic transcript originating from this locus, the gene is also co-transcribed with the upstream ZFP91 gene. Co-transcription from the two loci results in a transcript that contains a complete coding region for the zinc finger protein but lacks a complete coding region for ciliary neurotrophic factor.
    UniProt编号
    • P20294
    • P26441
    UniProt汇总 FUNCTION: SwissProt: P26441 # CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
    SIZE: 200 amino acids; 22931 Da
    SUBUNIT: Homodimer.
    SUBCELLULAR LOCATION: Cytoplasm.
    TISSUE SPECIFICITY: Nervous system.
    SIMILARITY: SwissProt: P26441 ## Belongs to the CNTF family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 The lyophilized powder, though stable at room temperature, is best stored desiccated below 0°C. Reconstitute with sterile water to a concentration of 100 mg/mL. This solution can be diluted into water or other buffered solutions. Reconstituted GF035 should be stored in undiluted aliquots at -20°C for up to six months.
    包装信息
    数量 25 µg

    merck millipore,默克密理博,GF035,Ciliary Neurotrophic Factor Protein, Recombinant rat

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