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merck millipore,默克密理博,ABC231,Anti-phospho DNM1L Antibody (Ser637)
产品名称:Anti-phospho DNM1L Antibody (Ser637)
产品型号:ABC231
Anti-phospho DNM1L Antibody (Ser637) is a highly specific rabbit polyclonal antibody, that targets Dynamin-like protein 1 & has been tested in western blotting & Peptide Inhibition Assay.
merck millipore,默克密理博,ABC231,Anti-phospho DNM1L Antibody (Ser637)
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC231 描述 Anti-phospho DNM1L Antibody (Ser637) Alternate Names - Dynamin-related protein 1
- Dynamin-1-like protein
- Dnm1p/Vps1p-like protein
- DVLP
- Dynamin family member proline-rich carboxyl-terminal domain less
- Dymple
- Dynamin-like protein
- Dynamin-like protein 4
- Dynamin-like protein IV
- HdynIV
背景信息 Dynamin-like protein 1 (DNM1L), also known as Dynamin related protein 1 (Drp1), mediates outer mitochondrial membrane fission in mammilian cells. Like other members of the Dynamin superfamily of GTPases, DNM1L contains a N-terminal tripartate GTP-binding domain and exists as a T-shaped dimer with a head, leg, and stalk. The addition of GTP induces head and stalk rearrangement resulting in membrane constriction. DNM1L has been shown to affect mitochondrial morphology and places a significant role in mitochondrial and peroxisomal fission in mammilian cells. During apoptosis, DNM1L translocates from the cytosol to mitochondria and localizes to potential organelle division sites. Studies show DNM1L inhibition averts cell death, reinforcing to the critical role that mitochondrial fission plays in apoptosis. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-phospho DNM1L Antibody (Ser637) is a highly specific rabbit polyclonal antibody, that targets Dynamin-like protein 1 & has been tested in western blotting & Peptide Inhibition Assay. 主要应用 - Western Blotting
应用说明 Peptide Inhibition Assay: A 1:1,000 dilution of this antibody detected phospho-DNM1L (Ser637) in 10 µg of forskolin treated PC-12 cell lysate. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the GSK3B interacting domain of human DNM1L phosphorylated at Ser637. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Rat Species Reactivity Note Demonstrated to react with Rat. Predicted to react with Human, Mouse, Chicken, Zebrafish, and Xenopus based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_005681
基因符号 - DRP1
- DNM1L
- DLP1
纯化方法 Affinity purified UniProt编号 - O00429
产品使用声明 质量保证 Evaluated by Western Blotting in forskolin treated PC-12 cell lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected phospho-DNM1L (Ser637) in 10 µg of forskolin treated PC-12 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
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