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merck millipore,默克密理博,FCMAB424F,Milli-Mark Anti-Chk2-FITC Antibody, clone 7
产品名称：Milli-Mark Anti-Chk2-FITC Antibody, clone 7
产品型号：FCMAB424F
Detect Milli-Mark Chk2-FITC using this Milli-Mark Anti-Chk2-FITC Antibody, clone 7 validated for use in Flow Cytometry.
merck millipore,默克密理博,FCMAB424F,Milli-Mark Anti-Chk2-FITC Antibody, clone 7
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H FC M FITC Monoclonal Antibody 描述 产品目录编号 FCMAB424F 商名 - Milli-Mark
描述 Milli-Mark® Anti-Chk2-FITC Antibody, clone 7 Alternate Names - serine/threonine-protein kinase CHK2
- CHK2 (checkpoint, S.pombe) homolog
- CHK2 checkpoint homolog (S. pombe)
- checkpoint-like protein CHK2
- protein kinase CHK2
背景信息 The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including Chk2, p53R2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. The checkpoint kinase Chk2 is the mammalian homologue of yeast Cds1/Rad53. In response to DNA damage, the checkpoint kinase ATM phosphorylates and activates Chk2, which in turn directly phosphorylates and activates p53. Chk2 serves as ATM downstream effector to mediate activation of p53. Chk2 also phosphorylates and activates BRCA1, the product of a tumor suppressor gene that is mutated in breast and ovarian cancer. 产品信息 格式 FITC 控制 - HeLa cells
演示 Purified mouse monoclonal IgG1 conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA. 应用 应用 Detect Milli-Mark Chk2-FITC using this Milli-Mark Anti-Chk2-FITC Antibody, clone 7 validated for use in Flow Cytometry. 主要应用 - Flow Cytometry
生物信息 免疫原品种 Mixture of two GST fusion proteins corresponding to residues 1-223 and 217-543 of human Chk2 克隆 7 宿主 Mouse 同种型 IgG1 品种反应性 Human Species Reactivity Note Demonstrated to react with Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_009125
基因符号 - Cds1
- CHEK2
- HuCds1
- CHK2
- LFS2
- RAD53
- bA444G7
- CDS1
- OTTHUMP00000028871
- PP1425
纯化方法 Protein G purified UniProt编号 - O96017
产品使用声明 质量保证 Evaluated by flow cytometry using HeLa cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt. 包装信息 数量 100 tests
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