merck millipore,默克密理愽
  • merck millipore,默克密理博,FCMAB302F,Milli-Mark™ Anti-Brachyury-FITC Antibody, clone 3E4.2

  • merck millipore,默克密理博,FCMAB302F,Milli-Mark™ Anti-Brachyury-FITC Antibody, clone 3E4.2

    产品名称：Milli-Mark™ Anti-Brachyury-FITC Antibody, clone 3E4.2
    产品型号：FCMAB302F
    Milli-Mark Anti-Brachyury-FITC Antibody, clone 3E4.2 is an antibody against Brachyury for use in FC.

    merck millipore,默克密理博,FCMAB302F,Milli-Mark™ Anti-Brachyury-FITC Antibody, clone 3E4.2

  • 产品介绍
  • merck millipore,默克密理博,FCMAB302F,Milli-Mark™ Anti-Brachyury-FITC Antibody, clone 3E4.2

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HFCMFITCMonoclonal Antibody
    描述
    产品目录编号 FCMAB302F
    商名
    • Milli-Mark
    描述 Milli-Mark™ Anti-Brachyury-FITC Antibody, clone 3E4.2
    Alternate Names
    • transcription factor T
    • T brachyury (mouse) homolog
    • T brachyury-like
    • T protein
    • T, brachyury homolog (mouse)
    背景信息 The Brachyury protein is a T-box transcription factor that is one of the earliest indicators of mesoderm formation during embryonic development. As the brachyury protein family is essential for the formation of the posterior body in all vertebrates, Brachyury has been shown to be expressed during gastrula and neurula stages, as well as in the developing notochord. Consequently, when mutations occur within the brachyury gene, severe vertebral malformations have been found to occur, as a direct result. In addition, current findings also indicate that the dysregulation of brachyury may also be linked to the formation of chordomas, which are malignant tumors that develop along the spine.
    产品信息
    格式 FITC
    控制
    • mouse ES cells (CMTI-2)
    演示 Purified mouse monoclonal IgG1k conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.
    应用
    应用 Milli-Mark Anti-Brachyury-FITC Antibody, clone 3E4.2 is an antibody against Brachyury for use in FC.
    主要应用
    • Flow Cytometry
    生物信息
    免疫原品种 Synthetic human brachyury peptide, a.a. 224-435.
    克隆 3E4.2
    宿主 Mouse
    特异性 Antibody recognizes Brachyury.
    同种型 IgG1κ
    品种反应性 Human
    Species Reactivity Note Tested and passed on Human.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_003172
    Entrez基因汇总 The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells.
    基因符号
    • TFT
    • MGC104817
    • OTTHUMP00000017588
    • TF
    纯化方法 Protein G Purified
    UniProt编号
    • O15178
    UniProt汇总 FUNCTION: SwissProt: O15178 # Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site.

    SIZE: 435 amino acids; 47443 Da

    SUBUNIT: Monomer (By similarity).

    Nucleus.

    DISEASE: SwissProt: O15178 # Genetic variations in T are associated with susceptibility to neural tube defects (NTD) [MIM:182940]. NTD are common congenital malformations. Spina bifida, which results from malformations in the caudal region of the neural tube, is compatible with life but associated with significant morbidity, including lower limb paralysis.

    SIMILARITY: SwissProt: O15178 ## Contains 1 T-box DNA-binding domain. ...
    产品使用声明
    质量保证 Evaluated by flow cytometry using mouse ES cells (CMTI-2)
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.
    包装信息
    数量 100 tests

    merck millipore,默克密理博,FCMAB302F,Milli-Mark™ Anti-Brachyury-FITC Antibody, clone 3E4.2

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