merck millipore,默克密理博,FCMAB169C5,Milli-Mark Anti-CD3 -PECy5 Antibody, clone UCHT1

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	FC	M	Phycoerythrin/Cy5	Monoclonal Antibody

描述
产品目录编号	FCMAB169C5
商名	Milli-Mark
描述	Milli-Mark Anti-CD3 -PECy5 Antibody, clone UCHT1
Alternate Names	T-cell receptor
背景信息	Human TCR/CD3 is a complex structure on the lymphocyte surface. It consists of the TCR alpha beta or TCR gamma delta heterodimer and the associated CD3 complex. The CD3 complex is composed of six polypeptides with usually four different transmembrane CD3 chains, gamma, delta, epsilon. and zeta. Three different dimers, gamma epsilon, delta epsilon, and zeta zeta, constitute the CD3 complex. The MW of CD3epsilon is 20 000 (Campana, 1987). CD3 is first detectable in early thymocytes and its appearance probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, during early stages of maturation, the CD3 antigen is predominantly present in the cell cytoplasm. In medullary thymocyles, the CD3 antigen is predominantly detected on the cell surface (Swerdlow, 1988; Beverley, 1981). The majority of T cell neoplasms also expresses CD3, but it is absent from non-T-cell lymphoid malignancies (McMichael, 1987). Consistent with the pattern of synthesis of the antigen in normal thymocytes, the earliest site detectable within neoplastic cells is the cell cytoplasm (Swerdlow, 1988).

产品信息
格式	Phycoerythrin/Cy5
控制	Human Lymphocytes
演示	Purified Mouse monoclonal IgG1 conjugated to PE/Cy5 in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2

应用
应用	This Milli-Mark Anti-CD3 -PECy5 Antibody, clone UCHT1 is validated for use in FC for the detection of CD3.
主要应用	Flow Cytometry

生物信息
免疫原品种	Human infant thymocytes and lymphocytes from a patient with Sézary disease.
克隆	UCHT1
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
特异性	Antibody recognizes Human CD3 antigen.
同种型	IgG1κ
品种反应性	Human
Species Reactivity Note	Human.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_932170.1
纯化方法	Protein A purfied
UniProt编号	P20963

产品使用声明
质量保证	Evaluated by flow cytometry using Human Lymphocytes.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

包装信息
数量	100 tests

merck millipore,默克密理博,FCMAB169C5,Milli-Mark Anti-CD3 -PECy5 Antibody, clone UCHT1

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