merck millipore,默克密理愽
  • merck millipore,默克密理博,196810,Bax-Inhibiting Peptide, V5 - Calbiochem

  • merck millipore,默克密理博,196810,Bax-Inhibiting Peptide, V5 - Calbiochem

    产品名称：Bax-Inhibiting Peptide, V5 - Calbiochem
    产品型号：196810
    A cell-permeable pentapeptide based on the Ku70-Bax inhibiting domain that offers cytoprotection.

    merck millipore,默克密理博,196810,Bax-Inhibiting Peptide, V5 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,196810,Bax-Inhibiting Peptide, V5 - Calbiochem

    重要规格表

    经验配方
    C₂₇H₅₀N₆O₆S
    描述
    概述 A cell-permeable pentapeptide based on the Ku70-Bax inhibiting domain that offers cytoprotection. Functions as effectively as the Caspase Inhibitor VI (Z-VAD-FMK; Cat. No. 219007) for Bax-mediated apoptosis (~50-200 µM). Also effectively blocks caspase-independent necrotic cell death. Shown to be Ku70 competitive, interact with Bax, prevent its conformational change and mitochondrial translocation. Displays extended stability in culture medium (~3 days). Negative control peptide is also available (Cat. No. 196811).
    产品目录编号 196810
    品牌系列 Calbiochem®
    同义词 BIP-V5, H-VPMLK-OH
    参考
    参考 Yoshida, T., et al. 2004. Biochem. Biophys. Res. Commun. 321, 961.
    Sawada, M., et al. 2003. Nature Cell Biol. 5, 352.
    产品信息
    具有ATP竞争性 N
    形式 White lyophilized solid
    配方 Supplied as a trifluoroacetate salt.
    Hill配方 C₂₇H₅₀N₆O₆S
    化学配方 C₂₇H₅₀N₆O₆S
    Molar Mass 586.8
    吸湿 Hygroscopic
    肽序列 H-Val-Pro-Met-Leu-Lys-OH
    可逆 N
    生物信息
    主靶 Bax mediated apoptosis
    主靶IC50 50-200 µM against Bax mediated apoptosis
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 H₂O
    肽序列 H-Val-Pro-Met-Leu-Lys-OH
    储存和货运信息
    货运代码 Blue Ice Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Storage in glass vials is not recommended as loss of activity may occur.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,196810,Bax-Inhibiting Peptide, V5 - Calbiochem

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下一件merck millipore产品：merck millipore,默克密理博,14-714,GRK5 Protein, active, 10 µg


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