merck millipore,默克密理愽
  • merck millipore,默克密理博,ABT267,Anti-CELSR3 Antibody

  • merck millipore,默克密理博,ABT267,Anti-CELSR3 Antibody

    产品名称：Anti-CELSR3 Antibody
    产品型号：ABT267
    Detect CELSR3 using this rabbit polyclonal antibody, Anti-CELSR3 Antibody validated for use in IHC.

    merck millipore,默克密理博,ABT267,Anti-CELSR3 Antibody

  • 产品介绍
  • merck millipore,默克密理博,ABT267,Anti-CELSR3 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHCRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 ABT267
    描述 Anti-CELSR3 Antibody
    Alternate Names
    • <br />Short name=Multiple EGF-like domains protein 2
    • Cadherin EGF LAG seven-pass G-type receptor 3
    • Cadherin family member 11
    • Epidermal growth factor-like protein 1
    • EGF-like protein 1
    • Flamingo homolog 1
    • hFmi1
    • Multiple epidermal growth factor-like domains protein 2
    背景信息 CELSR3, also known as Cadherin family member 11, Epidermal growth factor-like protein 1, EGF-like protein 1 or Flamingo homolog 1, FML1, or Multiple epidermal growth factor like domains protein 2, and encoded by the gene CELSR3/CDHF11, EGFL1, FMI1, KIAA0812, MEGF2, is a cell surface receptor important for cell to cell signaling and positioning particularly during the development of the nervous system. It is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined but may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation, and recent research demonstrates that CELSR3 is critical for proper development of GABA-signaling pathways in the inner retina. As a cadherin member, CELSR3 is localized to the cell membrane.
    产品信息
    格式 Affinity Purified
    演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Detect CELSR3 using this rabbit polyclonal antibody, Anti-CELSR3 Antibody validated for use in IHC.
    主要应用
    • Immunohistochemistry
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to the cytoplasmic domain within the C-terminus of human CELSR3.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    品种反应性 Human
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_001398
    基因符号
    • MEGF2
    • CELSR3
    • CDHF11
    • EGFL1
    • FMI1
    纯化方法 Affinity purified
    UniProt编号
    • Q9NYQ7
    产品使用声明
    质量保证 Evaluated by Immunohistochemistry in human cerebellum and glioma sections.

    Immunohistochemistry Analysis: A 1:2000 dilution and a 1:500 dilution of this antibody detected CELSR3 in human cerebellum and glioma sections, respectively.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,ABT267,Anti-CELSR3 Antibody

上一件merck millipore产品：merck millipore,默克密理博,06-923,Anti-Cdk1/Cdc2 (PSTAIR) Antibody
下一件merck millipore产品：merck millipore,默克密理博,200980,Bikinin - CAS 188011-69-0 - Calbiochem


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